Molecular structure of Tizoxanide, CAS Number: 173903-47-4
Tizoxanide (CAS 173903-47-4)
See product citations (1)
Alternate Names:
2-Hydroxy-N-(5-nitro-2-thiazolyl)benzamide; NSC 697856; TIZ; Desacetylnitazoxanide; Desacetyl Nitazoxanide
Application:
Tizoxanide is A potent inhibitor of hepatitis B virus and hepatitis C virus
CAS Number:
173903-47-4
Purity:
98%
Molecular Weight:
265.25
Molecular Formula:
C10H7N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus. Tizoxanide is also a metabolite of Nitazoxanide.
Tizoxanide (CAS 173903-47-4) References
- Efficient initiation of HCV RNA replication in cell culture. | Blight, KJ., et al. 2000. Science. 290: 1972-4. PMID: 11110665
- Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture. | Blight, KJ., et al. 2003. J Virol. 77: 3181-90. PMID: 12584342
- Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni. | Hoffman, PS., et al. 2007. Antimicrob Agents Chemother. 51: 868-76. PMID: 17158936
- Resistance of hepatitis C virus to NS3-4A protease inhibitors: mechanisms of drug resistance induced by R155Q, A156T, D168A and D168V mutations. | Courcambeck, J., et al. 2006. Antivir Ther. 11: 847-55. PMID: 17302247
- Tizoxanide Inhibits Inflammation in LPS-Activated RAW264.7 Macrophages via the Suppression of NF-κB and MAPK Activation. | Shou, J., et al. 2019. Inflammation. 42: 1336-1349. PMID: 30937840
- Analysis of tizoxanide, active metabolite of nitazoxanide, in rat brain tissue and plasma by UHPLC-MS/MS. | Guo, S., et al. 2020. Biomed Chromatogr. 34: e4716. PMID: 31633824
- Tizoxanide Promotes Apoptosis in Glioblastoma by Inhibiting CDK1 Activity. | Huang, S., et al. 2022. Front Pharmacol. 13: 895573. PMID: 35694267
- Tizoxanide Antiviral Activity on Dengue Virus Replication. | Yamamoto, KA., et al. 2023. Viruses. 15: PMID: 36992406
- Tizoxanide as a novel theraputic candidate for osteoarthritis. | Ni, B., et al. 2023. Heliyon. 9: e19472. PMID: 37662752
- Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group. | Allen, MI., et al. 1998. Hepatology. 27: 1670-7. PMID: 9620341
Inhibitor of:
SGLT-1, Sm N, and SRP54.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tizoxanide, 10 mg | sc-208441 | 10 mg | $380.00 |