Date published: 2026-4-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

Tiquizium Bromide (CAS 71731-58-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
HS 902; HSR 902; Thiaton; (5R,9aR)-rel-3-(Di-2-thienylmethylene)octahydro-5-methyl-2H-quinolizinium Bromide
CAS Number:
71731-58-3
Molecular Weight:
410.43
Molecular Formula:
C19H24NS2•Br
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Tiquizium Bromide has a notable affinity and non-selective action against muscarinic receptors, as determined through radioligand binding studies using 3H-quinuclidinyl benzilate. In experiments focusing on muscarinic receptors, it demonstrated characteristics akin to those of atropine, acting as a muscarinic antagonist. It showed 3-4 times greater potency towards muscarinic receptors compared to atropine. It exhibits oxidizing or reducing properties, depending on the specific circumstances, and can serve as a catalyst for facilitating desired product formation during organic reactions. Moreover, when combined with a suitable base, Tiquizium Bromide engages in reactions with other compounds, leading to the generation of novel chemical entities.


Tiquizium Bromide (CAS 71731-58-3) References

  1. [Case of anaphylaxis caused by tiquizium bromide (Thiaton)].  |  Osawa, K., et al. 1999. Nihon Naika Gakkai Zasshi. 88: 1524-6. PMID: 10475017
  2. [A case of famotidine-induced aseptic meningitis].  |  Ishihara, O. and Omata, T. 2000. Rinsho Shinkeigaku. 40: 48-50. PMID: 10825801
  3. Thioethers as urinary metabolites of thiophene and monobromothiophenes.  |  Hickman, RJ., et al. 1992. Xenobiotica. 22: 917-23. PMID: 1413881
  4. Treatment of functional dyspepsia with antianxiety or antidepressive agents: systematic review.  |  Hojo, M., et al. 2005. J Gastroenterol. 40: 1036-42. PMID: 16322947
  5. Inhibitory effect of ramosetron on corticotropin releasing factor- and soybean oil-induced delays in gastric emptying in rats.  |  Hirata, T., et al. 2012. J Gastroenterol Hepatol. 27: 1505-11. PMID: 22554268
  6. Ammonium acid urate urolithiasis in anorexia nervosa: a case report and literature review.  |  Fukai, M., et al. 2017. Clin Case Rep. 5: 685-687. PMID: 28469876
  7. [Cytoprotective activity of tiquizium bromide (HSR-902) and its mechanism].  |  Morikawa, K., et al. 1987. Nihon Yakurigaku Zasshi. 90: 285-93. PMID: 2895054
  8. A Case of Diffuse Esophageal Spasm Treated with Peroral Endoscopic Myotomy.  |  Sugihara, Y., et al. 2018. Acta Med Okayama. 72: 595-600. PMID: 30573915
  9. Adhesion-induced chronic abdominal pain: a case report on the diagnostic value of Carnett's test.  |  Kijima, T., et al. 2019. J Med Case Rep. 13: 93. PMID: 30999968
  10. Evidence-based clinical practice guidelines for irritable bowel syndrome 2020.  |  Fukudo, S., et al. 2021. J Gastroenterol. 56: 193-217. PMID: 33538894
  11. Studies on the affinity and selectivity of tiquizium bromide (HSR-902), a novel spasmolytic agent, for muscarinic receptors.  |  Oshita, M., et al. 1987. Jpn J Pharmacol. 44: 222-4. PMID: 3656779
  12. [Quantitative determination of tiquizium bromide in human serum and urine by reversed-phase high-performance liquid chromatography].  |  Yamada, T., et al. 1983. Yakugaku Zasshi. 103: 1319-22. PMID: 6677720
  13. [A study on the affinities of various muscarinic antagonists to the human detrusor muscle].  |  Kondo, S., et al. 1993. J Smooth Muscle Res. 29: 63-8. PMID: 8318731
  14. Antimuscarinic effect of tiquizium bromide in vitro and in vivo.  |  Shioya, T., et al. 1996. Eur J Clin Pharmacol. 50: 375-80. PMID: 8839659
  15. Disposition and metabolism of tenidap in the rat.  |  Fouda, HG., et al. 1997. Drug Metab Dispos. 25: 140-8. PMID: 9029043

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tiquizium Bromide, 100 mg

sc-474386
100 mg
$374.00