Molecular structure of TIQ-A, CAS Number: 420849-22-5
TIQ-A (CAS 420849-22-5)
See product citations (1)
Alternate Names:
Thieno[2,3-c]isoquinolin-5-one
Application:
TIQ-A is an inhibitor of poly(ADP-ribose) polyerase-1 (PARP-1)
CAS Number:
420849-22-5
Purity:
≥98%
Molecular Weight:
201.2
Molecular Formula:
C11H7NOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
TIQ-A is a potent PARP-1 (poly(ADP-ribose) polymerase-1) inhibitor, IC50=450nM). Neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells.
TIQ-A (CAS 420849-22-5) References
Chiarugi, A., et al.: J. Pharmacol. Exp. Ther., 305, 43 (2003), pellicciari, R., et al.: Farmaco., 58, 851 (2003) Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia: A. Chiarugi, et al.; J. Pharmacol. Exp. Ther. 305, 943 (2003) Towards new neuroprotective agents: design and synthesis of 4H-thieno[2,3-c] isoquinolin-5-one derivatives as potent PARP-1 inhibitors: R. Pellicciari, et al.; Farmaco 58, 851 (2003)Inhibitor of:
Enzyme, and PARP-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TIQ-A, 1 mg | sc-204916 | 1 mg | $68.00 | |||
TIQ-A, 5 mg | sc-204916A | 5 mg | $282.00 |