Molecular structure of Tiopronin, CAS Number: 1953-02-2
Tiopronin (CAS 1953-02-2)
Alternate Names:
N-(2-Mercaptopropionyl)glycine
Application:
Tiopronin is controls the rate of cystine precipitation and excretion
CAS Number:
1953-02-2
Molecular Weight:
163.19
Molecular Formula:
C5H9NO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tiopronin is a naturally occurring organic compound with a wide range of scientific applications. In laboratory experiments, it acts as a biological agent. In vitro studies involve using tiopronin in cell culture experiments, employing it as a substrate for enzyme assays, and utilizing it as an inhibitor for various enzymes. Notably, tiopronin has played a significant role in studying the activity of enzymes associated with carbohydrate, lipid, and protein metabolism. Additionally, it has been instrumental in investigating gene expression regulation and inhibiting certain enzymes that play a role in this process.
Tiopronin (CAS 1953-02-2) References
- Kinetics and mechanism of reactions of the drug tiopronin with platinum(IV) complexes. | Huo, S., et al. 2013. J Inorg Biochem. 125: 9-15. PMID: 23665090
- Determination of tiopronin based on the enhancement of Ru(bpy)₅²⁺ co-reactant electrochemiluminescence. | Kong, D., et al. 2015. Talanta. 134: 524-529. PMID: 25618703
- Influence of tiopronin, captopril and levamisole therapeutics on the oxidative degradation of hyaluronan. | Valachová, K., et al. 2015. Carbohydr Polym. 134: 516-23. PMID: 26428153
- Effect of tiopronin on excretion of homocysteine and its plasma exposure level in rats. | Miyajima, A., et al. 2016. Drug Metab Pharmacokinet. 31: 249-51. PMID: 27155909
- Influence of Tiopronin on the Metabolism of Alcohol in Healthy Subjects. | Nass, F., et al. 2017. Drug Res (Stuttg). 67: 204-210. PMID: 28142160
- Tiopronin in epilepsy. | Rose, GA. 1986. Lancet. 1: 452. PMID: 2868375
- Tiopronin-Protected Gold Nanoparticles as a Potential Marker for Cryo-EM and Tomography. | Dahan, I., et al. 2018. Structure. 26: 1408-1413.e3. PMID: 30078643
- Simultaneous determination of tiopronin and its primary metabolite in plasma and ocular tissues by HPLC. | Beltz, J., et al. 2019. Biomed Chromatogr. 33: e4375. PMID: 30176059
- Detection of tiopronin in body fluids and pharmaceutical products using red-emissive DNA-stabilized silver nanoclusters as a fluorescent probe. | Zhang, P., et al. 2019. Mikrochim Acta. 186: 609. PMID: 31392427
- Studies of the inhibitory activities of tiopronin and mercaptosuccinic acid on glutathione peroxidase and their cytotoxic and antioxidant properties. | Behnisch-Cornwell, S., et al. 2019. Pharmazie. 74: 536-542. PMID: 31484593
- Protective effects of tiopronin against oxidative stress in severely burned patients. | Qin, FJ., et al. 2019. Drug Des Devel Ther. 13: 2827-2832. PMID: 31496659
- The antioxidant N-(2-mercaptopropionyl)-glycine (tiopronin) attenuates expression of neuropathic allodynia and hyperalgesia. | Shahid, M., et al. 2021. Naunyn Schmiedebergs Arch Pharmacol. 394: 603-617. PMID: 33079239
- Tiopronin-induced membranous nephropathy in a patient with refractory familial cystinuria. | Micallef, S., et al. 2022. Br J Hosp Med (Lond). 83: 1-4. PMID: 36066303
- Tiopronin-induced lichenoid eruption. | Piérard, E., et al. 1994. J Am Acad Dermatol. 31: 665-7. PMID: 8089295
- Pharmacokinetics of oral tiopronin. | Carlsson, MS., et al. 1993. Eur J Clin Pharmacol. 45: 79-84. PMID: 8405034
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tiopronin, 1 g | sc-237114 | 1 g | $75.00 |