Tioclomarol (CAS 22619-35-8)
Alternate Names:
3-[3-(4-Chlorophenyl)-1-(5-chloro-2-thienyl)-3-hydroxypropyl]-4-hydroxy-2H-1-benzopyran-2-one; Apegmone; 3-[5-Chloro-α-(p-chloro-β-hydroxyphenethyl)-2-thenyl]-4-hydroxy-coumarin
CAS Number:
22619-35-8
Molecular Weight:
447.33
Molecular Formula:
C22H16Cl2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tioclomarol exhibits multiple beneficial properties, functioning as both an antioxidant and an anti-inflammatory agent. Its antioxidant role involves the scavenging of reactive oxygen species (ROS), which helps to counteract oxidative damage. Furthermore, Tioclomarol showcases its anti-inflammatory prowess by impeding the production of pro-inflammatory cytokines, thereby alleviating inflammatory responses. Tioclomarol has demonstrated its potential in inhibiting the growth of cancer cells. It achieves this by inducing cell cycle arrest, preventing uncontrolled cell division, and promoting apoptosis, a process of programmed cell death.
Tioclomarol (CAS 22619-35-8) References
- Validation of a new liquid chromatography- tandem mass spectrometry ion-trap technique for the simultaneous determination of thirteen anticoagulant rodenticides, drugs, or natural products. | Fourel, I., et al. 2010. J Anal Toxicol. 34: 95-102. PMID: 20223102
- Exploring adverse drug events at the class level. | Winnenburg, R., et al. 2015. J Biomed Semantics. 6: 18. PMID: 25937884
- Methods in food defence: a simple and robust screening for 16 rodenticides by LC-DAD/FLD following QuEChERS-based extraction. | Menacher, G., et al. 2022. Anal Bioanal Chem. 414: 5829-5836. PMID: 35715587
- Development and Validation of a Non-Targeted Screening Method for Most Psychoactive, Analgesic, Anaesthetic, Anti-Diabetic, Anti-Coagulant and Anti-Hypertensive Drugs in Human Whole Blood and Plasma Using High-Resolution Mass Spectrometry. | Feliu, C., et al. 2023. Pharmaceuticals (Basel). 16: PMID: 36678573
- Proposed classification of resistances to oral anticoagulant therapy. | Lefrere, JJ., et al. 1987. J Clin Pathol. 40: 242. PMID: 3818988
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tioclomarol, 10 mg | sc-475124 | 10 mg | $380.00 |