Date published: 2025-10-2

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Tin(IV) chloride (CAS 7646-78-8)

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Alternate Names:
Stannic chloride fuming
Application:
Tin(IV) chloride is a starting material for organotin compounds
CAS Number:
7646-78-8
Purity:
≥98%
Molecular Weight:
260.52
Molecular Formula:
SnCl4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tin(IV) chloride is involved in the synthesis of organic compounds. Tin(IV) chloride is a versatile reagent in biochemistry, as it can facilitate a wide range of chemical reactions, including acylation, alkylation, and condensation. It is used as a Lewis acid catalyst in the formation of carbon-carbon bonds, which is in the development of new agents. Tin(IV) chloride is employed in the modification of biomolecules, such as proteins and nucleic acids. Its ability to selectively modify specific functional groups makes it in bioconjugation and bioorthogonal chemistry. Tin(IV) chloride plays a significant role in the advancement of biochemistry.


Tin(IV) chloride (CAS 7646-78-8) References

  1. Tin(IV) chloride catalyzed cycloaddition reactions between 3-ethoxycyclobutanones and allylsilanes.  |  Matsuo, J., et al. 2009. Org Lett. 11: 3822-5. PMID: 19708696
  2. Tin (IV) chloride-promoted one-pot synthesis of novel tacrine analogues.  |  Hu, H., et al. 2011. Molecules. 16: 1878-87. PMID: 21343890
  3. Redetermination of di-μ-sulfido-bis-{[(2R)-2-acet-oxy-2-amino-ethane-1-thiol-ato-κN,S]oxidomolybdenum(V)}.  |  Akashi, H., et al. 2010. Acta Crystallogr Sect E Struct Rep Online. 66: m573. PMID: 21579054
  4. Observation by ESR of an acrylate radical conformationally locked by complexation with tin(IV) chloride.  |  Tanaka, H., et al. 1986. J Am Chem Soc. 108: 2208-11. PMID: 22175561
  5. Concerning the 1,5-stereocontrol in tin(IV) chloride promoted reactions of 4- and 5-alkoxyalk-2-enylstannanes: trapping intermediate allyltin trichlorides using phenyllithium.  |  Hobson, LA. and Thomas, EJ. 2012. Org Biomol Chem. 10: 7510-26. PMID: 22885896
  6. UV-visible spectroscopic estimation of photodegradation of rhodamine-B dye using tin(IV) oxide nanoparticles.  |  Sangami, G. and Dharmaraj, N. 2012. Spectrochim Acta A Mol Biomol Spectrosc. 97: 847-52. PMID: 22902583
  7. Synthesis of 2,4,5-trisubstituted oxazoles through tin(IV) chloride-mediated reaction of trans-2-aryl-3-nitro-cyclopropane-1,1-dicarboxylates with nitriles.  |  Selvi, T. and Srinivasan, K. 2014. Chem Commun (Camb). 50: 10845-8. PMID: 25090053
  8. Transformation of N, N-Dimethylaniline N-Oxides into Diverse Tetrahydroquinoline Scaffolds via Formal Povarov Reactions.  |  Bush, TS., et al. 2018. Org Lett. 20: 5406-5409. PMID: 30109939
  9. Photochemical Synthesis of Nanosheet Tin Di/Sulfide with Sunlight Response on Water Pollutant Degradation.  |  Matmin, J., et al. 2019. Nanomaterials (Basel). 9: PMID: 30769911
  10. Synthesis of Telmisartan Organotin(IV) Complexes and their use as Carbon Dioxide Capture Media.  |  Hadi, AG., et al. 2019. Molecules. 24: PMID: 31027205
  11. Long-Term Effect of Ultraviolet Irradiation on Poly(vinyl chloride) Films Containing Naproxen Diorganotin(IV) Complexes.  |  Hadi, AG., et al. 2019. Molecules. 24: PMID: 31261834
  12. SnCl4-catalyzed solvent-free acetolysis of 2,7-anhydrosialic acid derivatives.  |  Asressu, KH. and Wang, CC. 2019. Beilstein J Org Chem. 15: 2990-2999. PMID: 31949543
  13. Influence of Jatropha curcas seeds as a natural flocculant on reducing Tin (IV) tetrachloride in the treatment of concentrated stabilised landfill leachate.  |  Zainal, SFFS., et al. 2021. Chemosphere. 285: 131484. PMID: 34261011
  14. Tin(iv) chloride mediated (3 + 2) annulation of trans-2-aroyl-3-styrylcyclopropane-1,1-dicarboxylates with nitriles: diastereoselective access to 5-vinyl-1-pyrroline derivatives.  |  Thangamani, M., et al. 2021. RSC Adv. 11: 14980-14985. PMID: 35424056
  15. The atomic layer deposition (ALD) synthesis of copper-tin sulfide thin films using low-cost precursors.  |  Witkowski, M., et al. 2022. Nanotechnology. 33: PMID: 36075187

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tin(IV) chloride, 5 g

sc-251249
5 g
$47.00

Tin(IV) chloride, 25 g

sc-251249A
25 g
$136.00