Date published: 2025-12-10

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Tiglyl glycine (CAS 35842-45-6)

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Alternate Names:
N-[(2E)-2-Methyl-1-oxo-2-buten-1-yl]glycine; N-Tigloylglycine; N-Tiglylglycine
Application:
Tiglyl glycine is a metabolite of Isoleucine
CAS Number:
35842-45-6
Purity:
≥95%
Molecular Weight:
157.17
Molecular Formula:
C7H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tiglyl Glycine is a metabolite of Isoleucine.Tiglyl Glycine is a naturally occurring amino acid that is present in various plant and animal sources. It is a dietary component for humans and plays a significant role in numerous biochemical pathways. Extensive laboratory research has focused on Tiglyl Glycine, investigating its involvement in metabolism, potential applications in biotechnology, and its impact on biochemical and physiological processes. The laboratory studies on Tiglyl Glycine have delved into its role in metabolism, particularly its contribution to the synthesis of important metabolites like glutathione, cysteine, and taurine.


Tiglyl glycine (CAS 35842-45-6) References

  1. Methylmalonic and propionic acidurias: management without or with a few supplements of specific amino acid mixture.  |  Touati, G., et al. 2006. J Inherit Metab Dis. 29: 288-98. PMID: 16763890
  2. 1H-NMR studies of urine in propionic acidemia and methylmalonic acidemia.  |  Kodama, S., et al. 1991. Acta Paediatr Jpn. 33: 139-45. PMID: 1957637
  3. The first case of mitochondrial acetoacetyl-CoA thiolase deficiency identified by expanded newborn metabolic screening in Italy: the importance of an integrated diagnostic approach.  |  Catanzano, F., et al. 2010. J Inherit Metab Dis. 33 Suppl 3: S91-4. PMID: 20157782
  4. Clinical and biochemical characterization of four patients with mutations in ECHS1.  |  Ferdinandusse, S., et al. 2015. Orphanet J Rare Dis. 10: 79. PMID: 26081110
  5. Routine gas chromatographic/mass spectrometric analysis of urinary organic acids. Results over a three-year period.  |  Divry, P., et al. 1987. Biomed Environ Mass Spectrom. 14: 663-8. PMID: 2962675
  6. BRANCHED CHAIN AMINO ACIDS AT THE EDGE BETWEEN MENDELIAN AND COMPLEX DISORDERS.  |  Haydar, S., et al. 2018. Acta Endocrinol (Buchar). 14: 238-247. PMID: 31149264
  7. Analysis of urinary organic acids by Plasmaspray liquid chromatography/mass spectrometry.  |  Mills, GA., et al. 1988. Biomed Environ Mass Spectrom. 16: 259-61. PMID: 3242679
  8. Long-term follow-up with filter paper samples in patients with propionic acidemia.  |  Stanescu, S., et al. 2021. JIMD Rep. 57: 44-51. PMID: 33473339
  9. Multiple Carboxylase Deficiency Organic Acidemia as a Cause of Infantile Seizures.  |  Fatima, S., et al. 2021. J Coll Physicians Surg Pak. 31: 95-97. PMID: 33546543
  10. Severe anemia in patients with Propionic acidemia is associated with branched-chain amino acid imbalance.  |  Stanescu, S., et al. 2021. Orphanet J Rare Dis. 16: 226. PMID: 34006296
  11. Deficiency of propionyl-Co A carboxylase and methylcrotonyl-Co A carboxylase in a patient with methylcrotonylglycinuria.  |  Weyler, W., et al. 1977. Clin Chim Acta. 76: 321-8. PMID: 858206
  12. Synthesis and characterisation of acyl glycines. Their measurement in single blood spots by gas chromatography-mass spectrometry to diagnose inborn errors of metabolism.  |  Bonham Carter, SM., et al. 1996. J Chromatogr B Biomed Appl. 677: 29-35. PMID: 8925099

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tiglyl glycine, 50 mg

sc-213046A
50 mg
$306.00

Tiglyl glycine, 100 mg

sc-213046
100 mg
$367.00

Tiglyl glycine, 250 mg

sc-213046B
250 mg
$795.00

Tiglyl glycine, 500 mg

sc-213046C
500 mg
$1510.00

Tiglyl glycine, 1 g

sc-213046D
1 g
$2336.00