Molecular structure of Tiapride hydrochloride, CAS Number: 51012-33-0
Tiapride hydrochloride (CAS 51012-33-0)
Alternate Names:
N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-o-anisamide hydrochloride
Application:
Tiapride hydrochloride is a D2DR and D3DR inhibitor
CAS Number:
51012-33-0
Purity:
≥95%
Molecular Weight:
364.89
Molecular Formula:
C15H24N2O4S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tiapride hydrochloride is widely utilized in biochemical research, particularly in studies related to its interaction with dopamine receptors. This compound is used to explore the modulation of dopamine activity, which is critical for understanding the regulation of neurological and behavioral processes. Researchers apply Tiapride hydrochloride to investigate its effects on dopamine neurotransmission, aiding in the elucidation of mechanisms that control motor functions and emotional responses. Additionally, Tiapride hydrochloride is employed in neurochemical studies to assess its influence on receptor binding affinity and selectivity.
Tiapride hydrochloride (CAS 51012-33-0) References
- The preclinical pharmacologic profile of tiapride. | Scatton, B., et al. 2001. Eur Psychiatry. 16 Suppl 1: 29s-34s. PMID: 11520476
- Early administration of tiapride to young rats without long-lasting changes in the development of the dopaminergic system. | Bock, N., et al. 2004. Pharmacopsychiatry. 37: 163-7. PMID: 15467972
- Tiapride pre-treatment in acute exposure to paraoxon: comparison of effects of administration at different points-in-time in rats. | Petroianu, GA., et al. 2006. Mol Cell Biochem. 285: 79-86. PMID: 16479322
- Membrane sensors for the selective determination of tiapride in presence of its degradation products. | Metwally, FH. 2007. Yakugaku Zasshi. 127: 1267-73. PMID: 17666880
- Response of i(kr) and HERG currents to the antipsychotics tiapride and sulpiride. | Jo, SH. and Lee, SY. 2010. Korean J Physiol Pharmacol. 14: 305-10. PMID: 21165329
- Differential pulse anodic voltammetric determination of tiapride hydrochloride in pharmaceutical preparation and human urine using carbon paste electrodes. | Zayed, SI. 2011. Anal Sci. 27: 535. PMID: 21558662
- Tiapride for the treatment of auditory hallucinations in schizophrenia. | Karia, S., et al. 2013. Indian J Psychol Med. 35: 397-9. PMID: 24379503
- Tiapride is more effective and causes fewer adverse effects than risperidone in the treatment of senile dementia. | Yuan, Y., et al. 2016. Eur Rev Med Pharmacol Sci. 20: 3119-22. PMID: 27460743
- Unsuccessful Suicide Attempt With Tiapride. | Couderc, S., et al. 2017. Ther Drug Monit. 39: 581-583. PMID: 29135905
- Tiapride prevents the aversive but not the rewarding effect induced by parabrachial electrical stimulation in a place preference task. | Hurtado, MM., et al. 2017. Acta Neurobiol Exp (Wars). 77: 236-243. PMID: 29182614
- The Efficacy of Tiapride and Carbamazepine Combination Therapy in Reducing Alcohol Withdrawal Symptoms: A Systematic Review and Meta-Analysis. | Latifi, S. and Messer, T. 2019. Pharmacopsychiatry. 52: 209-216. PMID: 30522144
- Comprehensive systematic review summary: Treatment of tics in people with Tourette syndrome and chronic tic disorders. | Pringsheim, T., et al. 2019. Neurology. 92: 907-915. PMID: 31061209
- The DA-antagonist Tiapride affects context-related extinction learning in a predictive learning task, but not initial forming of associations, or renewal. | Klass, A., et al. 2021. Neurobiol Learn Mem. 183: 107465. PMID: 34015443
- Influence of Tiapride and Topiramate on Tic Severity and Behavioral/Emotional Problems in Children with Tourette Syndrome: A Retrospective Study. | Zhou, X., et al. 2023. Brain Sci. 13: PMID: 36979193
Inhibitor of:
D2DR, and D3DR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tiapride hydrochloride, 100 mg | sc-253697 | 100 mg | $90.00 |