Date published: 2025-12-18

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Tianeptine sodium salt (CAS 30123-17-2)

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Application:
Tianeptine sodium salt is a selective facilitator of serotonin uptake
CAS Number:
30123-17-2
Purity:
>99%
Molecular Weight:
458.93
Molecular Formula:
C21H24ClN2NaO4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation counter.


Tianeptine sodium salt (CAS 30123-17-2) References

  1. Analgesic effect of tianeptine in mice.  |  Uzbay, IT., et al. 1999. Life Sci. 64: 1313-9. PMID: 10227587
  2. Neuroprotective properties of tianeptine: interactions with cytokines.  |  Plaisant, F., et al. 2003. Neuropharmacology. 44: 801-9. PMID: 12681378
  3. The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers.  |  Grislain, L., et al. 1990. Drug Metab Dispos. 18: 804-8. PMID: 1981739
  4. Formulation of a novel tianeptine sodium orodispersible film.  |  El-Setouhy, DA. and Abd El-Malak, NS. 2010. AAPS PharmSciTech. 11: 1018-25. PMID: 20532710
  5. Tianeptine and its main metabolite. Disposition in chronic renal failure and haemodialysis.  |  Salvadori, C., et al. 1990. Fundam Clin Pharmacol. 4: 663-71. PMID: 2096105
  6. Pharmacokinetic and bioequivalence assessment of two formulations of tianeptine sodium in healthy male volunteers.  |  Zheng, R. and Kim, BH. 2014. Int J Clin Pharmacol Ther. 52: 817-23. PMID: 25109511
  7. Tianeptine sodium salt suppresses TNF-α-induced expression of matrix metalloproteinase-9 in human carcinoma cells via suppression of the PI3K/Akt-mediated NF-κB pathway.  |  Jayasooriya, RG., et al. 2014. Environ Toxicol Pharmacol. 38: 502-9. PMID: 25168152
  8. Tianeptine and its main metabolite pharmacokinetics in chronic alcoholism and cirrhosis.  |  Royer, RJ., et al. 1989. Clin Pharmacokinet. 16: 186-91. PMID: 2721088
  9. Neurochemical profile of tianeptine, a new antidepressant drug.  |  Kato, G. and Weitsch, AF. 1988. Clin Neuropharmacol. 11 Suppl 2: S43-50. PMID: 3052825
  10. Tianeptine, a selective enhancer of serotonin uptake in rat brain.  |  Mennini, T., et al. 1987. Naunyn Schmiedebergs Arch Pharmacol. 336: 478-82. PMID: 3437921

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tianeptine sodium salt, 10 mg

sc-204345
10 mg
$125.00

Tianeptine sodium salt, 50 mg

sc-204345A
50 mg
$560.00

I'm trying to understand the quantities sold. I'm wanting the 50 mg Tianeptine sodium salt. It says the molecular weight is 458. Is that grams? I just need to understanding of how much I'm getting for the cost? Please go into detail if you may.

Asked by: Taylor
Thank you for your question. The current sizes we offer are 10mg and 50mg. For a price quote and ship date please email scbt@scbt.com
Answered by: BlakeJ
Date published: 2024-09-11
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Rated 5 out of 5 by from KurodaKuroda, Y. et al. (PubMed 9729259) used tianeptine, a known antidepressant, to understand the mechanism by which it prevents atrophy of apical dendrites in the hippocampus of rats that have undergone chronic restraint stress. -SCBT Publication Review
Date published: 2015-03-19
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Tianeptine sodium salt is rated 5.0 out of 5 by 1.
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