Tianeptine Metabolite MC5-d4 Sodium Salt (CAS 1330171-36-2)
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Tianeptine Metabolite MC5-d4 Sodium Salt is a labeled, primary metabolite of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation counter.
Tianeptine Metabolite MC5-d4 Sodium Salt (CAS 1330171-36-2) References
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- Simultaneous determination of tianeptine and its active metabolite tianeptine MC5 in rat plasma and brain tissue using high performance liquid chromatography/electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) | El Zahar, N. M., Magdy, N., El-Kosasy, A. M., Beck, W. D., Callahan, P. M., Terry, A. V., & Bartlett, M. G. 2018. Analytical Methods. 10(4): 439-447.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tianeptine Metabolite MC5-d4 Sodium Salt, 1 mg | sc-220249 | 1 mg | $380.00 |