Molecular structure of Tianeptine-d12
Tianeptine-d12
Application:
Tianeptine-d12 is a deuterium-labeled analogue of Tianeptine
Molecular Weight:
449.03
Molecular Formula:
C21H13D12ClN2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tianeptine-d12 is a deuterium-labeled analogue of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation counter.
Tianeptine-d12 References
- Analgesic effect of tianeptine in mice. | Uzbay, IT., et al. 1999. Life Sci. 64: 1313-9. PMID: 10227587
- Neuroprotective properties of tianeptine: interactions with cytokines. | Plaisant, F., et al. 2003. Neuropharmacology. 44: 801-9. PMID: 12681378
- Neurochemical profile of tianeptine, a new antidepressant drug. | Kato, G. and Weitsch, AF. 1988. Clin Neuropharmacol. 11 Suppl 2: S43-50. PMID: 3052825
- Tianeptine, a selective enhancer of serotonin uptake in rat brain. | Mennini, T., et al. 1987. Naunyn Schmiedebergs Arch Pharmacol. 336: 478-82. PMID: 3437921
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tianeptine-d12, 500 µg | sc-220250 | 500 µg | $490.00 |