Date published: 2025-12-18

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Thyroxine-13C6 (CAS 1217780-14-7)

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Alternate Names:
O-(4-Hydroxy-3,5-diiodophenyl-13C6)-3,5-diiodo-L-tyrosine
Application:
Thyroxine-13C6 is a thyroid hormone involved in the maintenance of metabolic homeostasis
CAS Number:
1217780-14-7
Molecular Weight:
782.83
Molecular Formula:
(13C)6C9H11I4NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thyroxine-13C6 is a labeled analog of thyroxine, the main hormone produced by the thyroid gland. This variant of thyroxine is labeled with carbon-13 isotopes at six positions, which makes it valuable in various research applications that require the tracing and quantification of thyroxine metabolism and distribution. It is used in mass spectrometry-based studies for accurate and sensitive detection due to its distinct isotope pattern. In endocrinology research, Thyroxine-13C6 helps in elucidating the complex pathways of thyroid hormone regulation, transport, and action within biological systems. Additionally, it serves as a standard for calibrating analytical instruments and ensuring the precision of hormone measurements in various samples. The compound is also instrumental in studies investigating the effects of thyroxine on metabolic rate, growth, and development in organisms.


Thyroxine-13C6 (CAS 1217780-14-7) References

  1. Quantitative nephelometric assay for determining myoglobin evaluated.  |  Delanghe, JR., et al. 1990. Clin Chem. 36: 1675-8. PMID: 2208710
  2. Utilizing isotope dilution-matrix-assisted laser desorption ionization-time of flight mass spectrometry as a reference procedure for the radioimmunoassay of serum thyroxine.  |  Tyan, YC., et al. 2013. Clin Chim Acta. 420: 99-103. PMID: 23078848
  3. Direct determination of free thyroxin in undiluted serum by equilibrium dialysis/radioimmunoassay.  |  Nelson, JC. and Tomei, RT. 1988. Clin Chem. 34: 1737-44. PMID: 3138040
  4. Reference Intervals of Thyroid Function Tests Assessed by Immunoassay and Mass Spectrometry in Healthy Pregnant Women Living in Catalonia.  |  Hernández, JM., et al. 2021. J Clin Med. 10: PMID: 34072898
  5. Physiological variations in thyroid hormones: physiological and pathophysiological considerations.  |  Fisher, DA. 1996. Clin Chem. 42: 135-9. PMID: 8565215
  6. Iodine metabolism and thyroid physiology: current concepts.  |  Cavalieri, RR. 1997. Thyroid. 7: 177-81. PMID: 9133680

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thyroxine-13C6, 1 mg

sc-220244
1 mg
$632.00