Molecular structure of Thymoquinone, CAS Number: 490-91-5
Thymoquinone (CAS 490-91-5)
See product citations (21)
Alternate Names:
2-Isopropyl-5-methyl-1,4-benzoquinone
Application:
Thymoquinone is a phytochemical that inhibitis tumor angiogenesis
CAS Number:
490-91-5
Purity:
≥98%
Molecular Weight:
164.20
Molecular Formula:
C10H12O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Thymoquinone is a phytochemical compound that acts as an angiogenesis inhibitor. Possesses potential analgesic, anticonvulsant, and anticancer properties in vitro.
Thymoquinone (CAS 490-91-5) References
- Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels. | Gilhotra, N. and Dhingra, D. 2011. Pharmacol Rep. 63: 660-9. PMID: 21857076
- Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets. | Kundu, J., et al. 2014. Food Chem Toxicol. 65: 18-26. PMID: 24355171
- Thymoquinone treatment against acetaminophen-induced hepatotoxicity in rats. | Aycan, IÖ., et al. 2014. Int J Surg. 12: 213-8. PMID: 24389315
- Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis. | Ashour, AE., et al. 2014. Mol Cell Biochem. 389: 85-98. PMID: 24399465
- Protective effect of thymoquinone on glucose or methylglyoxal-induced glycation of superoxide dismutase. | Khan, MA., et al. 2014. Int J Biol Macromol. 65: 16-20. PMID: 24412154
- Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model. | Siveen, KS., et al. 2014. Oncotarget. 5: 634-48. PMID: 24504138
- Protective role of thymoquinone against paraquat-induced hepatotoxicity in mice. | Zeinvand-Lorestani, H., et al. 2018. Pestic Biochem Physiol. 148: 16-21. PMID: 29891368
- Effects of Thymoquinone on radiation enteritis in mice. | Hou, Q., et al. 2018. Sci Rep. 8: 15122. PMID: 30310156
- Thymoquinone ameliorates age-related hearing loss in C57BL/6J mice by modulating Sirt1 activity and Bak1 expression. | Salam, SA., et al. 2021. Biomed Pharmacother. 143: 112149. PMID: 34507120
- Thymoquinone ameliorates bleomycin-induced reproductive toxicity in male Balb/c mice. | Yaghutian Nezhad, L., et al. 2021. Hum Exp Toxicol. 40: S611-S621. PMID: 34818114
Inhibitor of:
β-defensin 2, AIP1, Angiogenesis, Dtl, KRTAP10-9, Mps1, NAT-15, Olfr830, SPANX-B2, SPANX-FI, Syndecan-1, T2R20, T2R29, TMEM202, TRAF6, V1RC24, V1RC32, V1rc5, XPC, and ZNF98.Activator of:
ANAPC2, CD30, connexin 37, Cyclin D1, cylindromatosis 1, Cyp4f16, demethylated-PP2A-C, Drebrin, EG432879, EG624855, FBXW24, H-plk, HAX-1, Hep C NS3, IL-18, IL-1RAcP, Lex A, LMP7, LRP1B, NELF-E, PI 3-kinase p110δ, POLDIP3, PR3, RecQL1, RFX5, RIPX, SATB1, Snk, TERT, TMCO7, Tollip, TRIM35, TRPV3, UBE2E1, USP9X, VSTM1, XPG, ZFP161, ZNF629, and ZNF843.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thymoquinone, 1 g | sc-215986 | 1 g | $46.00 | |||
Thymoquinone, 5 g | sc-215986A | 5 g | $130.00 |