Molecular structure of Thymine, CAS Number: 65-71-4
Thymine (CAS 65-71-4)
Alternate Names:
2,4-Dihydroxy-5-methylpyrimidine; 5-Methyluracil
Application:
Thymine is a nucleobase found in deoxyribonucleic acids (DNA)
CAS Number:
65-71-4
Purity:
≥99%
Molecular Weight:
126.11
Molecular Formula:
C5H6N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Thymine is one of the four nucleobases, along with adenine, guanine and cytosine found in deoxyribonucleic acids (DNA). Thymine may be used to study chemical processes that affect DNA structure, such a radiation induced radical production leading to base cross-linking reactions and derivitizations. Thymine may be used to study the parameters of hydrogen bonding kinetics and energies with other nucleobases such as adenine. Thymine is used to develop sensitive heavy metal (mercury) detectors based on coordination chemistry and nanoparticle structures.
Thymine (CAS 65-71-4) References
- A thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+/Na+ ions. | Cáceres, C., et al. 2004. Nucleic Acids Res. 32: 1097-102. PMID: 14960719
- Photodissociation of thymine. | Schneider, M., et al. 2006. Phys Chem Chem Phys. 8: 3017-21. PMID: 16880915
- Conical intersections in thymine. | Perun, S., et al. 2006. J Phys Chem A. 110: 13238-44. PMID: 17149840
- Photophysics and deactivation pathways of thymine. | Zechmann, G. and Barbatti, M. 2008. J Phys Chem A. 112: 8273-9. PMID: 18707067
- Designing of MIP based QCM sensor having thymine recognition sites based on biomimicking DNA approach. | Diltemiz, SE., et al. 2009. Biosens Bioelectron. 25: 599-603. PMID: 19250816
- Thymine, adenine and lipoamino acid based gene delivery systems. | Skwarczynski, M., et al. 2010. Chem Commun (Camb). 46: 3140-2. PMID: 20424753
- Quantitative analysis of thymine with surface-enhanced Raman spectroscopy and partial least squares (PLS) regression. | Zhang, L., et al. 2010. Anal Bioanal Chem. 398: 1827-32. PMID: 20721540
- Impact of thymine glycol damage on DNA duplex energetics: Correlations with lesion-induced biochemical and structural consequences. | Minetti, CA., et al. 2015. Biopolymers. 103: 491-508. PMID: 25991500
- Mechanisms for the formation of thymine under astrophysical conditions and implications for the origin of life. | Bera, PP., et al. 2016. J Chem Phys. 144: 144308. PMID: 27083722
- Preliminary Evidence for Enhanced Thymine Absorption: A Putative New Phenotype Associated With Fluoropyrimidine Toxicity in Cancer Patients. | Duley, JA., et al. 2018. Ther Drug Monit. 40: 495-502. PMID: 29846282
- The Behavior of Triplet Thymine in a Model B-DNA Strand. Energetics and Spin Density Localization Revealed by ab initio Molecular Dynamics Simulations. | Allahkaram, L., et al. 2022. Photochem Photobiol. 98: 633-639. PMID: 34699615
- Photocrosslinking Probes Proximity of Thymine Modifiers Tethering Excitonically Coupled Dye Aggregates to DNA Holliday Junction. | Basu, S., et al. 2022. Molecules. 27: PMID: 35807250
- -irradiation of thymine dimers in aqueous solution. | Deering, RA. and Snipes, W. 1968. Biophys J. 8: 326-36. PMID: 4934290
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thymine, 5 g | sc-296545 | 5 g | $38.00 | |||
Thymine, 10 g | sc-296545A | 10 g | $43.00 | |||
Thymine, 100 g | sc-296545B | 100 g | $112.00 | |||
Thymine, 250 g | sc-296545C | 250 g | $196.00 |