Date published: 2026-3-14

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Thioxanthone (CAS 492-22-8)

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Alternate Names:
9-Oxothioxanthene
CAS Number:
492-22-8
Purity:
≥99%
Molecular Weight:
212.27
Molecular Formula:
C13H8OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thioxanthone, a derivative of xanthone, holds a significant role in various scientific research domains, particularly in the realms of photochemistry and biochemistry. Within the realm of photochemistry, it serves as a valuable photosensitizer, facilitating photochemical reactions like the photobleaching of dyes. In the field of biochemistry, it finds use as an enzyme inhibitor and a fluorescent marker for proteins. Furthermore, in materials science, it serves as a precursor for polymer synthesis and a dopant for semiconductor materials. Thioxanthone′s notable property lies in its capacity to act as a photosensitizer, absorbing light energy and subsequently transferring it to a specific target molecule. This transfer initiates a chemical reaction that has the potential to give rise to the formation of a new molecule.


Thioxanthone (CAS 492-22-8) References

  1. Thioxanthone: on the shape of the first absorption band.  |  Rai-Constapel, V., et al. 2010. Phys Chem Chem Phys. 12: 9320-7. PMID: 20607180
  2. Endocrine-disrupting effects of thioxanthone photoinitiators.  |  Reitsma, M., et al. 2013. Toxicol Sci. 132: 64-74. PMID: 23208609
  3. Thioxanthone hydroquinone-O,O'-diacetic acid: photoinitiator or photostabilizer?  |  Karasu, F., et al. 2013. J Org Chem. 78: 9161-5. PMID: 23944866
  4. A chiral thioxanthone as an organocatalyst for enantioselective [2+2] photocycloaddition reactions induced by visible light.  |  Alonso, R. and Bach, T. 2014. Angew Chem Int Ed Engl. 53: 4368-71. PMID: 24648167
  5. Thioxanthone in apolar solvents: ultrafast internal conversion precedes fast intersystem crossing.  |  Mundt, R., et al. 2016. Phys Chem Chem Phys. 18: 6637-47. PMID: 26868771
  6. Structure-Performance Investigation of Thioxanthone Derivatives for Developing Color Tunable Highly Efficient Thermally Activated Delayed Fluorescence Emitters.  |  Wang, Z., et al. 2016. ACS Appl Mater Interfaces. 8: 8627-36. PMID: 27003610
  7. Spectrophotometric study on binding of 2-thioxanthone acetic acid with ct-DNA.  |  Ataci, N., et al. 2018. Spectrochim Acta A Mol Biomol Spectrosc. 204: 281-286. PMID: 29945110
  8. Silicone-Thioxanthone: A Multifunctionalized Visible Light Photoinitiator with an Ability to Modify the Cured Polymers.  |  Wu, Q., et al. 2019. Polymers (Basel). 11: PMID: 30995770
  9. Cytotoxic effects of thioxanthone derivatives as photoinitiators on isolated rat hepatocytes.  |  Nakagawa, Y., et al. 2020. J Appl Toxicol. 40: 234-244. PMID: 31633820
  10. A Thioxanthone Sensitizer with a Chiral Phosphoric Acid Binding Site: Properties and Applications in Visible Light-Mediated Cycloadditions.  |  Pecho, F., et al. 2020. Chemistry. 26: 5190-5194. PMID: 32065432
  11. Thioxanthone: a powerful photocatalyst for organic reactions.  |  Nikitas, NF., et al. 2021. Org Biomol Chem. 19: 5237-5253. PMID: 34047729
  12. Discovery of a Thioxanthone-TfOH Complex as a Photoredox Catalyst for Hydrogenation of Alkenes Using p-Xylene as both Electron and Hydrogen Sources.  |  Kang, WJ., et al. 2022. Angew Chem Int Ed Engl. 61: e202211562. PMID: 36107463
  13. Unraveling the Efficiency of Thioxanthone Based Triplet Sensitizers: A Detailed Theoretical Study.  |  Chandra Garain, B. and Pati, SK. 2023. Chemphyschem. 24: e202200753. PMID: 36495016
  14. Effect of Substituents with the Different Electron-Donating Abilities on Optoelectronic Properties of Bipolar Thioxanthone Derivatives.  |  Macionis, S., et al. 2023. ACS Appl Electron Mater. 5: 2227-2238. PMID: 37124238

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thioxanthone, 50 g

sc-281170
50 g
$130.00