Date published: 2026-4-1

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Thiourea (CAS 62-56-6)

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Alternate Names:
Sulfourea; Thiocarbamide
Application:
Thiourea is a chaotropic agent
CAS Number:
62-56-6
Molecular Weight:
76.12
Molecular Formula:
CH4N2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thiourea, also known as thiocarbamide, is a colorless and water-soluble organic compound. In scientific applications, thiourea is utilized as a reagent in organic synthesis, playing a role as a catalyst for the synthesis of organic compounds. It also acts as a reducing agent in the synthesis of inorganic compounds. Thiourea exhibits nucleophilic properties, allowing it to react with electrophiles like carbonyl compounds and halides. This reaction yields thiourea derivatives that can further participate in subsequent reactions with other compounds. Thiourea can function as a reducing agent, effectively converting aldehydes and ketones into alcohols.


Thiourea (CAS 62-56-6) References

  1. (Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators.  |  Sharma, SK., et al. 2010. J Med Chem. 53: 5197-212. PMID: 20568780
  2. Molecular structure of thiourea.  |  Puzzarini, C. 2012. J Phys Chem A. 116: 4381-7. PMID: 22471631
  3. Preparation of new type of organocatalysts having a carbohydrate scaffold.  |  Agoston, K. and Fügedi, P. 2014. Carbohydr Res. 389: 50-6. PMID: 24680505
  4. Thiourea-based fluorescent chemosensors for aqueous metal ion detection and cellular imaging.  |  Vonlanthen, M., et al. 2014. J Org Chem. 79: 6054-60. PMID: 24957917
  5. Organophotocatalysis: Insights into the Mechanistic Aspects of Thiourea-Mediated Intermolecular [2+2] Photocycloadditions.  |  Vallavoju, N., et al. 2016. Angew Chem Int Ed Engl. 55: 5446-51. PMID: 27005562
  6. Allylic isothiouronium salts: The discovery of a novel class of thiourea analogues with antitumor activity.  |  Ferreira, M., et al. 2017. Eur J Med Chem. 129: 151-158. PMID: 28222315
  7. Inhibiting fly ash reactivity by adding N- and S- containing compounds.  |  Soler, A., et al. 2018. Chemosphere. 211: 294-301. PMID: 30077109
  8. Investigation on the effect of alkyl chain linked mono-thioureas as Jack bean urease inhibitors, SAR, pharmacokinetics ADMET parameters and molecular docking studies.  |  Larik, FA., et al. 2019. Bioorg Chem. 86: 473-481. PMID: 30772648
  9. Synthesis and antiproliferative screening of novel doubly modified colchicines containing urea, thiourea and guanidine moieties.  |  Krzywik, J., et al. 2021. Bioorg Med Chem Lett. 47: 128197. PMID: 34116158
  10. Anion-binding of a chiral tris(2-aminoethyl)amine-based tripodal thiourea: a spectroscopic and computational study.  |  Scholten, K. and Merten, C. 2022. Phys Chem Chem Phys. 24: 4042-4050. PMID: 35103733
  11. Cationic dinitrosyl iron complexes with thiourea exhibit selective toxicity to brain tumor cells in vitro.  |  Sanina, NA., et al. 2022. Dalton Trans. 51: 8893-8905. PMID: 35635550
  12. Synthesis and Identification of New N,N-Disubstituted Thiourea, and Thiazolidinone Scaffolds Based on Quinolone Moiety as Urease Inhibitor.  |  Elshaier, YAMM., et al. 2022. Molecules. 27: PMID: 36296723
  13. Preparative two-dimensional gel electrophoresis of membrane proteins.  |  Pasquali, C., et al. 1997. Electrophoresis. 18: 2573-81. PMID: 9527487
  14. Subcellular fractionation of polarized epithelial cells and identification of organelle-specific proteins by two-dimensional gel electrophoresis.  |  Fialka, I., et al. 1997. Electrophoresis. 18: 2582-90. PMID: 9527488
  15. Use of thiourea to increase the solubility of membrane proteins in two-dimensional electrophoresis.  |  Rabilloud, T. 1998. Electrophoresis. 19: 758-60. PMID: 9629911

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thiourea, 50 g

sc-213038
50 g
$38.00