Thioridazine 5-Sulfoxide (CAS 7776-05-8)
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Thioridazine 5-sulfoxide is a compound primarily used in analytical chemistry for the study of oxidation mechanisms and metabolic pathways related to sulfur-containing organics. Its role as a metabolite analog allows researchers to investigate the sulfoxidation processes that occur in various substances. In environmental chemistry, Thioridazine 5-sulfoxide serves as a reference compound to understand the transformation and degradation patterns of related chemicals when exposed to different environmental conditions. Additionally, it is used in the field of biochemistry to study enzyme-substrate interactions, particularly with those enzymes involved in sulfoxide metabolism. The compound is also utilized in spectroscopy as a standard for calibrating instruments and confirming the identity of sulfoxide-containing compounds in complex mixtures.
Thioridazine 5-Sulfoxide (CAS 7776-05-8) References
- Study on thioridazine 5-sulfoxide epimerization and degradation by capillary electrophoresis. | Masetto de Gaitani, C., et al. 2003. Electrophoresis. 24: 2723-30. PMID: 12900889
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- Stereoselective analysis of thioridazine-2-sulfoxide and thioridazine-5-sulfoxide: an investigation of rac-thioridazine biotransformation by some endophytic fungi. | Borges, KB., et al. 2008. J Pharm Biomed Anal. 46: 945-52. PMID: 17614234
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- Cardiotoxicity of thioridazine and two stereoisomeric forms of thioridazine 5-sulfoxide in the isolated perfused rat heart. | Hale, PW. and Poklis, A. 1986. Toxicol Appl Pharmacol. 86: 44-55. PMID: 3764935
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- Thioridazine 5-sulfoxide diastereoisomers in serum and urine from rats and man after chronic thioridazine administration. | Hale, PW. and Poklis, A. 1985. J Anal Toxicol. 9: 197-201. PMID: 4057956
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- Determination of diastereoisomeric pairs of thioridazine 5-sulfoxide by high-performance liquid chromatography. | Hale, PW. and Poklis, A. 1984. J Chromatogr. 336: 452-5. PMID: 6530479
- Thioridazine-5-sulfoxide cardiotoxicity in the isolated, perfused rat heart. | Hale, PW. and Poklis, A. 1984. Toxicol Lett. 21: 1-8. PMID: 6719481
- Thioridazine and its metabolites in post mortem blood, including two stereoisomeric ring sulfoxides. | Poklis, A., et al. 1982. J Anal Toxicol. 6: 250-2. PMID: 7176556
- Determination of the enantiomers of thioridazine, thioridazine 2-sulfone, and of the isomeric pairs of thioridazine 2-sulfoxide and thioridazine 5-sulfoxide in human plasma. | Eap, CB., et al. 1995. J Chromatogr B Biomed Appl. 669: 271-9. PMID: 7581903
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thioridazine 5-Sulfoxide, 5 mg | sc-213037 | 5 mg | $398.00 |