Date published: 2026-4-4

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Thionyl bromide (CAS 507-16-4)

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CAS Number:
507-16-4
Molecular Weight:
207.87
Molecular Formula:
SOBr2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thionyl bromide stands as a colorless liquid widely employed in laboratory experiments and industrial processes. With its potent oxidizing properties, thionyl bromide participates in various reactions, notably contributing to the synthesis of sulfones, sulfonamides, and sulfonic acids. The scientific community heavily relies on thionyl bromide, particularly in the realm of organic synthesis. It also plays a significant role in polymer synthesis, as well as the manufacturing of lubricants and various industrial products. Thionyl bromide acts as a potent oxidizing agent, thereby facilitating a wide range of reactions. When subjected to hydrolysis in the presence of an acid, thionyl bromide readily transforms into sulfuric acid and bromine. This hydrolysis reaction serves as a key step in the synthesis of sulfonamides and sulfonic acids.


Thionyl bromide (CAS 507-16-4) References

  1. One-pot synthesis of 4,8-dibromobenzo[1,2-c;4,5-c']bis[1,2,5]thiadiazole.  |  Tam, TL., et al. 2010. Org Lett. 12: 3340-3. PMID: 20614912
  2. Synthesis of Halogenated Anilines by Treatment of N, N-Dialkylaniline N-Oxides with Thionyl Halides.  |  Reed, H., et al. 2018. J Org Chem. 83: 11359-11368. PMID: 30048135
  3. Room-Temperature, Metal-Free, and One-Pot Preparation of 2H-Indazoles through a Mills Reaction and Cyclization Sequence.  |  Kondo, M., et al. 2019. Chemistry. 25: 9866-9869. PMID: 31150138
  4. Preparation and preliminary biological evaluation of [18F]NCQ-115: a new selective reversible dopamine D2 receptor ligand.  |  Najafi, A., et al. 1993. Nucl Med Biol. 20: 549-55. PMID: 8504293

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thionyl bromide, 25 g

sc-253696
25 g
$72.00