Molecular structure of ThioFluor 623, CAS Number: 1004324-99-5
ThioFluor 623 (CAS 1004324-99-5)
Alternate Names:
Fluorescent Thiol Probe
Application:
ThioFluor 623 is a fluorescent thiol-reactive probe
CAS Number:
1004324-99-5
Purity:
≥98%
Molecular Weight:
678.67
Molecular Formula:
C31H30N6O10S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Thiofluor 623 responds upon exposure to thiols with an increase in fluorescence intensity of up to 120-fold. The response is selective for thiols and occurs in aqueous media. In the absence of thiols, the probe is essentially non-fluorescent; thiols cause cleavage of the probe, making a fluorophore with an absorption maximum of 563 nm and emission at 623 nm. The fluorescence quantum yield of the cleaved product, generated in response to thiols, increases in more viscous media, suggesting ideal performance in biological systems and applicability to single-molecule or 2-photon sensing schemes. The thiofluor 623 is cell-permeable and reacts selectively with intracellular thiols.
ThioFluor 623 (CAS 1004324-99-5) References
1 Bouffard, J., Kim, Y., Swager, T.M., et al. A highly selective fluorescent probe for thiol bioimaging. Organic Lett 10(1) 37-40 (2008)Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ThioFluor 623, 5 mg | sc-205524 | 5 mg | $357.00 | |||
ThioFluor 623, 10 mg | sc-205524A | 10 mg | $612.00 |