Thielavin A CAS: 71950-66-8
MF: C29H30O10
MW: 538.5
Apotent prostaglandin synthetase inhibitor.

Thielavin A (CAS 71950-66-8)

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Application: Thielavin A is apotent prostaglandin synthetase inhibitor
CAS Number: 71950-66-8
Purity: >94%
Molecular Weight: 538.5
Molecular Formula: C29H30O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Thielavin A is a potent Cox (prostaglandin, PG synthetase) inhibitor derived from Thielavia terricola. Studies show that Thielavins A inhibits the transformation of arachinodic acid into prostaglandin H2 (sc-201266). Thielavins A and B (sc-202362) are composed of three hydroxybenzoic acid groups and are structurally related to depsides. Thielavin A is an inhibitor of G6Pase.


References

1. Kitahara, N., et al. 1981. J. Antibiot. 34: 1562-1568. PMID: 7333968
2. Kitahara, N., et al. 1983. J. Antibiot. 36: 599-600. PMID: 6409872
3. Sakemi, S., et al. 2002. J. Antibiot. 55: 941-951. PMID: 12546415

Physical State :
Solid
Solubility :
Soluble in methanol, and DMSO.
Storage :
Store at -20° C
Boiling Point :
849.97° C at 760 mmHg (Predicted)
Density :
1.37 g/cm3 (Predicted)
Refractive Index :
n20D 1.65 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
194424
MDL Number :
MFCD11111622
SMILES :
CC1=CC(=C(C(=C1C(=O)OC2=C(C(=C(C(=C2C)O)C(=O)OC3=C(C(=C(C(=C3C)O)C(=O)O)C)C)C)C)O)C)O

Download SDS (MSDS)

Certificate of Analysis

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