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Thiamine, Hydrochloride (CAS 67-03-8)

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Alternate Names:
Aneurine hydrochloride; Vitamin B1hydrochloride
Application:
Thiamine, Hydrochloride is a cofactor required for oxidation of carbohydrates and for the synthesis of ribose
CAS Number:
67-03-8
Molecular Weight:
337.27
Molecular Formula:
C12H17N4OSCl•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thiamine, Hydrochloride, a water-soluble vitamin belonging to the B vitamin group, exhibits several noteworthy properties. It serves as a model system for studying the phase transition temperature of fatty acids in biological membranes. Furthermore, Thiamine, Hydrochloride has demonstrated the ability to enhance thermal expansion and improve chronic exposure in fetal bovine brain cells. Its insecticidal activity has been observed against various insect species, such as the tobacco budworm and the Indianmeal moth. Thiamine, Hydrochloride actively participates in cellular metabolism by facilitating the conversion of l-lysine into succinic acid through an intermediate called anthranilate. Moreover, it plays a vital role in pyridoxal phosphate synthesis, a component for protein synthesis and tissue growth. Thiamine, Hydrochloride is a cofactor required for oxidation of carbohydrates and for the synthesis of ribose.


Thiamine, Hydrochloride (CAS 67-03-8) References

  1. Treatment with thiamine hydrochloride and astaxanthine for the prevention of yolk-sac mortality in Baltic salmon fry (M74 syndrome).  |  Koski, P., et al. 1999. Dis Aquat Organ. 37: 209-20. PMID: 10546051
  2. Polymorphic changes of thiamine hydrochloride during granulation and tableting.  |  Wöstheinrich, K. and Schmidt, PC. 2001. Drug Dev Ind Pharm. 27: 481-9. PMID: 11548854
  3. Effect of thiamine hydrochloride, pyridoxine hydrochloride and calcium-d-pantothenate on the patulin content of apple juice concentrate.  |  Yazici, S. and Velioglu, YS. 2002. Nahrung. 46: 256-7. PMID: 12224421
  4. A toxicity study of parenteral thiamine hydrochloride.  |  Wrenn, KD., et al. 1989. Ann Emerg Med. 18: 867-70. PMID: 2757284
  5. The Effects of Thiamine Hydrochloride on Cardiac Function, Redox Status and Morphometric Alterations in Doxorubicin-Treated Rats.  |  Radonjic, T., et al. 2020. Cardiovasc Toxicol. 20: 111-120. PMID: 31270735
  6. Thiamine hydrochloride as a recyclable organocatalyst for the synthesis of bis(indolyl)methanes, tris(indolyl)methanes, 3,3-di(indol-3-yl)indolin-2-ones and biscoumarins.  |  Mathavan, S., et al. 2019. Org Biomol Chem. 17: 9620-9626. PMID: 31664290
  7. The Effect of Thiamine Concentration on the Antioxidative Activity Indices in Tea Extracts.  |  Piechocka, J., et al. 2019. Antioxidants (Basel). 8: PMID: 31731638
  8. A Pilot Clinical Study on Thiamine Hydrochloride as a New Mosquito Repellent: Determination of the Minimum Effective Dose on Human Skin.  |  Badawi, A., et al. 2020. Biol Pharm Bull. 43: 284-288. PMID: 32009117
  9. Efficient and Green Synthesis of Bis(indolyl)Methanes using Thiamine Hydrochloride as an Organocatalyst: A Parallel Scrutiny of Microwave Irradiation versus Ultrasonicator Heating in Water.  |  Thorat, NM., et al. 2020. Curr Org Synth. 17: 679-684. PMID: 32562525
  10. The Potential of a Site-Specific Delivery of Thiamine Hydrochloride as a Novel Insect Repellent Exerting Long-Term Protection on Human Skin: In-vitro, Ex-vivo Study and Clinical Assessment.  |  Halawany, ME., et al. 2021. J Pharm Sci. 110: 3659-3669. PMID: 34358530
  11. Monitoring of glutathione using ratiometric fluorescent sensor based on MnO2 nanosheets simultaneously tuning the fluorescence of Rhodamine 6G and thiamine hydrochloride.  |  Zhang, T., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 271: 120942. PMID: 35114634
  12. Constructing a defect-rich hydroxide nanoenzyme sensor based on dielectric barrier discharge microplasma etching for sensitive detection of thiamine hydrochloride and hydrogen peroxide.  |  Hu, P., et al. 2022. J Colloid Interface Sci. 628: 597-606. PMID: 35940144
  13. In Vivo Evaluation of Thiamine Hydrochloride with Gastro-Retentive Drug Delivery in Healthy Human Volunteers Using Gamma Scintigraphy.  |  Kam, LY., et al. 2023. Pharmaceutics. 15: PMID: 36840013

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thiamine, Hydrochloride, 100 g

sc-205859
100 g
$93.00

Thiamine, Hydrochloride, 250 g

sc-205859A
250 g
$195.00

Thiamine, Hydrochloride, 1 kg

sc-205859B
1 kg
$526.00

Thiamine, Hydrochloride, 25 kg

sc-205859C
25 kg
$5106.00

Thiamine, Hydrochloride, 100 kg

sc-205859D
100 kg
$20406.00

what is the purity of the current lot of the thiamine hydrochloride

Asked by: Jules s
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot.
Answered by: Tech Service
Date published: 2019-06-10
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Rated 5 out of 5 by from Consistant and reliableSanta cruz has been our supplier of this product for some time and we find the quality of the product and delivery service to be excellent.
Date published: 2021-10-08
Rated 5 out of 5 by from Good delivery timesFast delivery service,way faster than the estimated delivery date
Date published: 2020-10-28
Rated 5 out of 5 by from JiJi, Z. et al. (PubMed 25063874) reported that Thiamine deficiency promotes T cell infiltration in experimental autoimmune encephalomyelitis. -SCBT Publication Review
Date published: 2015-01-24
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Thiamine, Hydrochloride is rated 5.0 out of 5 by 3.
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