Molecular structure of TGF-β RI Kinase Inhibitor VII, CAS Number: 666729-57-3
TGF-β RI Kinase Inhibitor VII (CAS 666729-57-3)
Application:
TGF-β RI Kinase Inhibitor VII is an inhibitor of ALK5/TGF-β Receptor I kinase activity
CAS Number:
666729-57-3
Molecular Weight:
351.4
Molecular Formula:
C21H21NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
TGF-β RI Kinase Inhibitor VII is a compound used extensively in cellular and molecular biology to study the transforming growth factor-beta (TGF-β) signaling pathway. By specifically inhibiting the TGF-β type I receptor kinase, this inhibitor allows for the exploration of the diverse roles of TGF-β signaling in cell proliferation, differentiation, and apoptosis. Research with TGF-β RI Kinase Inhibitor VII is for dissecting the pathway′s contribution to the regulation of the extracellular matrix, immune function, and angiogenesis. It is also used to investigate the TGF-β pathway′s involvement in fibrosis and the epithelial-to-mesenchymal transition.
TGF-β RI Kinase Inhibitor VII (CAS 666729-57-3) References
- Synthesis and evaluation of [2-(4-quinolyloxy)phenyl]methanone derivatives: novel selective inhibitors of transforming growth factor-beta kinase. | Shimizu, T., et al. 2008. J Med Chem. 51: 3326-9. PMID: 18479116
Inhibitor of:
TGF beta RI.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TGF-β RI Kinase Inhibitor VII, 5 mg | sc-356133 | 5 mg | $250.00 |