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TFIIIC102 Antibody (X-421) is a mouse monoclonal IgG2b antibody that detects TFIIIC102 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). TFIIIC102 plays a crucial role in the transcription of RNA polymerase III, which is essential for synthesizing various small RNAs, including tRNA and 5S rRNA, that are vital for protein synthesis and cellular function. TFIIIC102 functions as part of the TFIIIC2 complex, which recruits RNA polymerase III and the TFIIIB transcription factor complex to promoter elements, facilitating the transcription process. Dysregulation of TFIIIC102 and associated complexes can lead to aberrant cell growth and proliferation, often observed in transformed and malignant cells, such as those found in ovarian carcinomas. Overexpression of TFIIIC102 in these cells highlights potential as a biomarker for cancer progression and a target for therapeutic intervention. Anti-TFIIIC102 antibody (X-421) serves as an invaluable tool for researchers studying RNA polymerase III transcription mechanisms and cancer biology implications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TFIIIC102 Antibody (X-421) | sc-101176 | 50 µg/0.5 ml | $339.00 |