Texas Red-2-sulfonamidoethyl methanethiosulfonate (CAS 386229-76-1)

Texas Red-2-sulfonamidoethyl methanethiosulfonate serves as a highly valuable water-soluble organic compound in various scientific research applications. This red fluorescent dye finds extensive use in labeling proteins and other biomolecules for imaging and tracking within cell biology and biochemistry studies. Notably, Texas Red-2-sulfonamidoethyl methanethiosulfonate presents numerous advantages over other fluorescent dyes, including its high fluorescence quantum yield, low cytotoxicity, and long-wavelength emission. In scientific research, Texas Red-2-sulfonamidoethyl methanethiosulfonate plays a vital role across diverse applications. Researchers employ it in fluorescence microscopy and flow cytometry to effectively label proteins and biomolecules for visualization and monitoring purposes. Moreover, Texas Red-2-sulfonamidoethyl methanethiosulfonate finds utility in a range of biophysical and biochemical assays, such as ELISA, Western blotting, and enzyme assays, where its unique properties prove beneficial. The fluorescence of Texas Red-2-sulfonamidoethyl methanethiosulfonate emerges when it undergoes excitation by blue light, resulting in the emission of red light. This striking characteristic arises from its distinctive structure, encompassing a sulfonamidoethyl methanethiosulfonate (SMT) molecule at the core, complemented by two substituents—a 4-hydroxy-3-methoxybenzylamine (HMB) and an ethyl group. The presence of the SMT molecule contributes to the red fluorescence, while the HMB and ethyl groups play a critical role in enhancing the dye′s solubility in aqueous solutions. As a consequence, Texas Red-2-sulfonamidoethyl methanethiosulfonate serves as an invaluable tool in scientific research for its ability to facilitate precise and non-toxic imaging and tracking of biomolecules.