Molecular structure of Tetramisole hydrochloride, CAS Number: 5086-74-8
Tetramisole hydrochloride (CAS 5086-74-8)
Alternate Names:
(±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
Application:
Tetramisole hydrochloride is an inhibitor of alkaline phosphatases
CAS Number:
5086-74-8
Purity:
≥99%
Molecular Weight:
240.75
Molecular Formula:
C11H12N2S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tetramisole hydrochloride is suitable for inhibition of various alkaline phosphatase (i.e., liver, kidney, placenta, bone and tumor)(Intestinal alkaline phosphatases are only slightly inhibited.) Used to treat worm and roundworm infections. Inhibits enzyme activity of tissue culture cells by binding to sulfhydryl group of cysteine residues at enzyme active site. Also inhibits sodium carbonate-stimulated ATPase activity.
Tetramisole hydrochloride (CAS 5086-74-8) References
- Facile colorimetric methods for the quantitative determination of tetramisole hydrochloride. | Amin, AS. and Dessouki, HA. 2002. Spectrochim Acta A Mol Biomol Spectrosc. 58: 2541-6. PMID: 12396035
- [Anthelminthic Effectiveness Of 2,3,5,6-Tetrahydro 6-Phenyl-Imidazole (2,1-B) Thiazole Hydrochloride (=tetramisole) Upon Intestinal Parasites]. | Kim, CH. and Soh, CT. 1970. Kisaengchunghak Chapchi. 8: 48-50. PMID: 12913513
- Potentiometric sensor for the high throughput determination of tetramisole hydrochloride. | Gupta, VK., et al. 2007. Comb Chem High Throughput Screen. 10: 583-94. PMID: 17979641
- An extractive spectrophotometric method for the determination of tetramisole hydrochloride in pharmaceutical preparations. | Sane, RT., et al. 1985. Talanta. 32: 148-9. PMID: 18963812
- Stereodivergent organocatalytic intramolecular Michael addition/lactonization for the asymmetric synthesis of substituted dihydrobenzofurans and tetrahydrofurans. | Belmessieri, D., et al. 2014. Chemistry. 20: 9762-9. PMID: 24989672
- Stimulation of anti-Brucella vaccination in mice by tetramisole, a phenyl-imidothiazole salt. | Renoux, G. and Renoux, M. 1973. Infect Immun. 8: 544-8. PMID: 4200541
- [Comparison of affects of bephenium hydroxynaphthoate, tetramisole hydrochloride and tetramisole pamoate in the treatment of Ancylostoma duodenale and Necator americanus infections]. | . 1973. Zhonghua Yi Xue Za Zhi. 8: 490-1. PMID: 4200747
- Efficacy and safety of l-tetramisole hydrochloride in experimental Cooperia punctata infection of dairy calves. | Alicata, JE. and Furumoto, HH. 1969. Am J Vet Res. 30: 139-41. PMID: 5812435
- [Udder compatibility of tetramisole and levamisole hydrochloride and suggestion for the prescription of their intramammary use in cattle against Prototheca zopfii]. | Bergmann, A. 1993. Berl Munch Tierarztl Wochenschr. 106: 253-6. PMID: 8216186
- [Imidazo(2,1-b)thiazole XII derivatives. Synthesis and research of immunoactivity in vitro on human T lymphocyte of 3-aroylmethyl and 2-aroyl-3-methyl(aryl)-5,6-dihydroimidaz o(2,1-b)thiazoles]. | Robert, JF., et al. 1995. Ann Pharm Fr. 53: 261-71. PMID: 8572506
Inhibitor of:
Alkaline Phosphatase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tetramisole hydrochloride, 2 g | sc-215963 | 2 g | $46.00 | |||
Tetramisole hydrochloride, 5 g | sc-215963A | 5 g | $71.00 |