Molecular structure of Tetrahydrozoline hydrochloride, CAS Number: 522-48-5
Tetrahydrozoline hydrochloride (CAS 522-48-5)
Alternate Names:
4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole Hydrochloride; Murine Plus
Application:
Tetrahydrozoline hydrochloride is an α activator in the constriction of conjuctival blood vessels
CAS Number:
522-48-5
Molecular Weight:
236.74
Molecular Formula:
C13H16N2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tetrahydrozoline hydrochloride is a compound that functions as a vasoconstrictor. It acts by stimulating alpha-adrenergic receptors in the smooth muscle of blood vessels, leading to constriction of the vessels. This constriction reduces the flow of blood to the area where the compound is applied. At the molecular level, tetrahydrozoline hydrochloride binds to and activates alpha-adrenergic receptors, triggering a cascade of intracellular events that ultimately result in vasoconstriction. Tetrahydrozoline Hydrochloride′s mechanism of action involves its interaction with specific receptors on the smooth muscle cells. Tetrahydrozoline hydrochloride can be used to investigate the effects of vasoconstriction on various biological processes.
Tetrahydrozoline hydrochloride (CAS 522-48-5) References
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- Severe respiratory depression following nasal instillation of tetrahydrozoline hydrochloride. | CHUSID, E., et al. 1956. J Pediatr. 48: 66-9. PMID: 13295949
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- Clinical trial of tetrahydrozoline hydrochloride; a valuable new nasal decongestant. | NEISTADT, I. 1955. AMA Arch Otolaryngol. 62: 143-4. PMID: 14397923
- Simple HPLC determination of benzalkonium chloride in ophthalmic formulations containing antazoline and tetrahydrozoline. | Rojsitthisak, P., et al. 2005. PDA J Pharm Sci Technol. 59: 332-7. PMID: 16316068
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- Stability-Indicating RP-HPLC Methods for the Determination of Fluorometholone in Its Mixtures with Sodium Cromoglycate and Tetrahydrozoline Hydrochloride. | El-Bagary, RI., et al. 2016. J Chromatogr Sci. 54: 923-33. PMID: 26921897
- Stability-Indicating HPLC Method for Simultaneous Determination of Chloramphenicol, Dexamethasone Sodium Phosphate and Tetrahydrozoline Hydrochloride in Ophthalmic Solution. | AlAani, H. and Alnukkary, Y. 2016. Adv Pharm Bull. 6: 137-41. PMID: 27123429
- Development and validation of a reversed-phase HPLC method for analysis of tetrahydrozoline hydrochloride in eye drop formulations. | Al-Rimawi, F., et al. 2012. J Pharm Anal. 2: 67-70. PMID: 29403723
- An electrochemical sensing platform to determine tetrahydrozoline HCl in pure form, pharmaceutical formulation, and rabbit aqueous humor. | Mahmoud, AM., et al. 2020. Anal Methods. 12: 2903-2913. PMID: 32930213
- Simultaneous high-performance liquid chromatographic determination of antazoline phosphate and tetrahydrozoline hydrochloride in ophthalmic solution. | Puglisi, G., et al. 1986. J Chromatogr. 369: 165-70. PMID: 3793827
- Stability-indicating determination of tetrahydrozoline hydrochloride in ophthalmic solutions by high-performance liquid chromatography. | Andermann, G. and Richard, A. 1984. J Chromatogr. 298: 189-92. PMID: 6480751
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IRE1β.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tetrahydrozoline hydrochloride, 1 g | sc-213023 | 1 g | $40.00 |