Molecular structure of Tetrahydrofuran, CAS Number: 109-99-9
Tetrahydrofuran (CAS 109-99-9)
Alternate Names:
THF
Application:
Tetrahydrofuran is a heterocyclic polar solvent and polymer precursor
CAS Number:
109-99-9
Purity:
≥99%
Molecular Weight:
72.11
Molecular Formula:
C4H8O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tetrahydrofuran is a heterocyclic polar solvent and polymer precursor. It is a aprotic and water miscible solvent used in Grignard syntheses or lithium aluminium hydride reductions. Tetrahydrofuran (THF) is a colorless liquid with the chemical formula C4H8O. Classified as a cyclic ether, it possesses a sweet odor and is highly flammable. In numerous industries, such as pharmaceuticals, chemicals, and food, Tetrahydrofuran serves as a valuable solvent. It finds extensive use in organic chemistry as a solvent, reaction medium, and reagent, aiding various organic reactions and synthesis processes. Moreover, it holds significance in scientific research applications, including polymer synthesis, serving as a reaction medium and solvent for polymerization reactions.
Tetrahydrofuran (CAS 109-99-9) References
- Tetrahydrofuran degradation by a newly isolated culture of Pseudonocardia sp. strain K1. | Kohlweyer, U., et al. 2000. FEMS Microbiol Lett. 186: 301-6. PMID: 10802188
- Tetrahydrofuran: two-generation reproduction toxicity in Wistar rats by continuous administration in the drinking water. | Hellwig, J., et al. 2002. Food Chem Toxicol. 40: 1515-23. PMID: 12387317
- Aggregation of alkyllithiums in tetrahydrofuran. | Pratt, LM., et al. 2007. J Org Chem. 72: 2962-6. PMID: 17358078
- Tetra-mu-acetato-bis{[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]rhodium(II)}(Rh-Rh) tetrahydrofuran tetrasolvate. | André, V., et al. 2008. Acta Crystallogr C. 64: m345-8. PMID: 18838768
- The cationic ring-opening polymerization of tetrahydrofuran with 12-tungstophosphoric acid. | Aouissi, A., et al. 2010. Molecules. 15: 1398-407. PMID: 20335988
- Glycosylation initiated cationic ring-opening polymerization of tetrahydrofuran to prepare neo-glycopolymers. | Li, Y. and Yu, B. 2010. Chem Commun (Camb). 46: 6060-2. PMID: 20657930
- Synthesis and anti-tumor activity of carbohydrate analogues of the tetrahydrofuran containing acetogenins. | Bachan, S., et al. 2013. Bioorg Med Chem. 21: 6554-64. PMID: 24045006
- Enantio- and diastereoselective assembly of tetrahydrofuran and tetrahydropyran skeletons with all-carbon-substituted quaternary stereocenters. | Chen, Z. and Sun, J. 2013. Angew Chem Int Ed Engl. 52: 13593-6. PMID: 24254193
- Reaction of chlorine radical with tetrahydrofuran: a theoretical investigation on mechanism and reactivity in gas phase. | Begum, S. and Subramanian, R. 2014. J Mol Model. 20: 2262. PMID: 24867438
- Biodegradation kinetics of tetrahydrofuran, benzene, toluene, and ethylbenzene as multi-substrate by Pseudomonas oleovorans DT4. | Chen, DZ., et al. 2014. Int J Environ Res Public Health. 12: 371-84. PMID: 25561017
- Study of Electron Ionization and Fragmentation of Non-hydrated and Hydrated Tetrahydrofuran Clusters. | Neustetter, M., et al. 2017. J Am Soc Mass Spectrom. 28: 866-872. PMID: 28326462
- Sodium Diisopropylamide in Tetrahydrofuran: Selectivities, Rates, and Mechanisms of Alkene Isomerizations and Diene Metalations. | Algera, RF., et al. 2017. J Am Chem Soc. 139: 11544-11549. PMID: 28735535
- Novel tetrahydrofuran (THF) degradation-associated genes and cooperation patterns of a THF-degrading microbial community as revealed by metagenomic. | Qi, M., et al. 2019. Chemosphere. 231: 173-183. PMID: 31129398
- Efficiency of Lithium Cations in Hydrolysis Reactions of Esters in Aqueous Tetrahydrofuran. | Hayashi, K., et al. 2021. Chem Pharm Bull (Tokyo). 69: 581-584. PMID: 33790075
- Cometabolic degradation of 1,4-dioxane by a tetrahydrofuran-growing Arthrobacter sp. WN18. | Wang, P., et al. 2021. Ecotoxicol Environ Saf. 217: 112206. PMID: 33866286
Activator of:
Fullerene.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tetrahydrofuran, 100 ml | sc-222349 | 100 ml | $45.00 | |||
Tetrahydrofuran, 1 L | sc-222349A | 1 L | $100.00 |