Tetrahydrobiopterin (THB) dihydrochloride (CAS 69056-38-8)
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Tetrahydrobiopterin (THB) dihydrochloride is an activating Nitric Oxide Synthase (NOS) cofactor used in a variety of applications. Tetrahydrobiopterin (THB) dihydrochloride is also a known cofactor for the monooxygenases that hydroxylate phenylalanine, tyrosine, and tryptophan. Synthesis of Tetrahydrobiopterin (THB) dihydrochloride has been documented to be the rate limiting step in the metabolism of phenylalanine and the biosynthesis of neurotransmiter amines. In mice, Quinolinic acid (sc-203226) induced convulsions that were potentiated with Tetrahydrobiopterin dihydrochloride, demonstrating that endogenous NO may be involved in stimulating the NMDA receptors. When hypertensive mice were fed Tetrahydrobiopterin (THB) dihydrochloride but were not introduced to hydralazine or tetrahydroneopterin, they displayed improved cardiac Tetrahydrobiopterin (THB) dihydrochloride stores, phosphorylated phospholamban levels, and diastolic dysfunction. Tetrahydrobiopterin (THB) dihydrochloride has also been observed as an essential cofactor in the hydroxylation process in mammalian brains.
Tetrahydrobiopterin (THB) dihydrochloride (CAS 69056-38-8) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tetrahydrobiopterin (THB) dihydrochloride, 25 mg | sc-200345 | 25 mg | $83.00 | |||
Tetrahydrobiopterin (THB) dihydrochloride, 100 mg | sc-200345A | 100 mg | $204.00 |