Date published: 2026-2-18

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Tetraethylene glycol monododecyl ether (CAS 5274-68-0)

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Alternate Names:
Dodecyltetraglycol
Application:
Tetraethylene glycol monododecyl ether is a well-characterized and non-ionic surfactant
CAS Number:
5274-68-0
Purity:
≥98%
Molecular Weight:
362.54
Molecular Formula:
C20H42O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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TEGDME, short for tetraethylene glycol monododecyl ether, is a non-ionic surfactant utilized in both industrial and laboratory applications. This colorless, odorless liquid exhibits a low vapor pressure and low toxicity. Tetraethylene glycol monododecyl ether is adept at modifying the surface tension of liquids, enhancing their wetting properties. Tetraethylene glycol monododecyl ether (TEGDME) for its multitude of applications. Its presence is notable in cell culture and enzyme assays. Tetraethylene glycol monododecyl ether has in solubilizing and stabilizing proteins, peptides, and other biomolecules. It serves as useful in studying the impact of surfactants on cell membranes and proteins. The action of Tetraethylene glycol monododecyl ether (TEGDME) manifests as a surfactant, which effectively reduces the surface tension of liquids while enhancing their wetting properties. This effect is attributed to the formation of micelles—aggregates of molecules that effectively decrease the liquid′s surface tension. These micelles act as solubilizing agents, augmenting the solubility of hydrophobic molecules within the liquid.


Tetraethylene glycol monododecyl ether (CAS 5274-68-0) References

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  6. Preparation of calcium alginate nanoparticles using water-in-oil (W/O) nanoemulsions.  |  Machado, AH., et al. 2012. Langmuir. 28: 4131-41. PMID: 22296569
  7. Spontaneous transformation of lamellar structures from simple to more complex states.  |  Dou, Y., et al. 2013. Langmuir. 29: 12901-8. PMID: 24070426
  8. Magnetic-field-induced orientational phase structure transition.  |  Dou, Y., et al. 2014. Langmuir. 30: 1266-71. PMID: 24447257
  9. Lyotropic La-containing lamellar liquid crystals: phase behaviour, thermal and structural properties.  |  Selivanova, NM., et al. 2015. Soft Matter. 11: 7809-16. PMID: 26314681
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  14. Interaction of surfactants with barley leaf surfaces: time-dependent recovery of contact angles is due to foliar uptake of surfactants.  |  Baales, J., et al. 2021. Planta. 255: 1. PMID: 34837118

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetraethylene glycol monododecyl ether, 1 ml

sc-281576
1 ml
$163.00

Tetraethylene glycol monododecyl ether, 5 ml

sc-281576A
5 ml
$444.00