Date published: 2026-4-29

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Tetraethylene glycol (CAS 112-60-7)

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Alternate Names:
Tetraglycol
CAS Number:
112-60-7
Purity:
≥98%
Molecular Weight:
194.23
Molecular Formula:
C8H18O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetraethylene glycol (TEG), a polyether glycol, is a colorless, odorless, and slightly viscous liquid characterized by a low freezing point. With its versatile nature, Tetraethylene glycol holds a prominent position in the realm of industrial chemistry, finding extensive applications as a solvent, lubricant, and intermediate compound in the production of diverse chemicals. In the realm of scientific research, Tetraethylene glycol has been subject to thorough investigation for its potential applications. Although the exact mechanism of action of Tetraethylene glycol remains a subject of ongoing study, its interactions with cell membranes, proteins, and enzymes are known to play a role.


Tetraethylene glycol (CAS 112-60-7) References

  1. Phase behavior of the mixtures of poly(oxyethylene) (10) stearyl ether (Brij-76), 1-butanol, isooctane, and mixed polar solvents II. Water and ethylene glycol (EG) or tetraethylene glycol (TEG).  |  Nandy, D., et al. 2007. J Colloid Interface Sci. 310: 229-39. PMID: 17346729
  2. Multiprobe spectroscopic evidence for 'hyperpolarity' within 1-butyl-3-methylimidazolium hexafluorophosphate mixtures with tetraethylene glycol.  |  Sarkar, A., et al. 2008. J Phys Chem B. 112: 14927-36. PMID: 18954101
  3. Modulation of enzyme-substrate selectivity using tetraethylene glycol functionalized gold nanoparticles.  |  Jordan, BJ., et al. 2009. Nanotechnology. 20: 434004. PMID: 19801753
  4. A mild and efficient method for the selective deprotection of silyl ethers using KF in the presence of tetraethylene glycol.  |  Yan, H., et al. 2011. Org Biomol Chem. 9: 8119-21. PMID: 21986770
  5. Solvatochromic probe response within ionic liquids and their equimolar mixtures with tetraethylene glycol.  |  Rai, R. and Pandey, S. 2014. J Phys Chem B. 118: 11259-70. PMID: 25162184
  6. Blue Electrogenerated Chemiluminescence from Water-Soluble Iridium Complexes Containing Sulfonated Phenylpyridine or Tetraethylene Glycol Derivatized Triazolylpyridine Ligands.  |  Kerr, E., et al. 2015. Chemistry. 21: 14987-95. PMID: 26334026
  7. A tetraethylene glycol coat gives gold nanoparticles long in vivo half-lives with minimal increase in size.  |  Willett, JD., et al. 2017. Int J Nanomedicine. 12: 2581-2592. PMID: 28408825
  8. Switching on the proton transport pathway of a lanthanide metal-organic framework by one-pot loading of tetraethylene glycol for high proton conduction.  |  Wang, X., et al. 2018. Dalton Trans. 47: 9096-9102. PMID: 29938261
  9. New Modified Deoxythymine with Dibranched Tetraethylene Glycol Stabilizes G-Quadruplex Structures.  |  Tateishi-Karimata, H., et al. 2020. Molecules. 25: PMID: 32041318
  10. Water-Soluble Iridium(III) Complexes Containing Tetraethylene-Glycol-Derivatized Bipyridine Ligands for Electrogenerated Chemiluminescence Detection.  |  Newman, B., et al. 2020. Front Chem. 8: 583631. PMID: 33195075
  11. Photodynamic inactivation of Staphylococcus aureus using tetraethylene glycol-substituted Zn(II) phthalocyanine.  |  Mete, E., et al. 2021. Biotech Histochem. 96: 311-314. PMID: 33325738
  12. The effect of D-(+)-glucosamine, N-acetyl-D-glucosamine and tetraethylene glycol on the stability of oxytocin in aqueous solution.  |  Ghasemisarabbadieh, M., et al. 2021. Pharmazie. 76: 480-483. PMID: 34620274
  13. Rhenium(I) conjugates as tools for tracking cholesterol in cells.  |  Lazniewska, J., et al. 2022. Metallomics. 14: PMID: 35657681
  14. Bacterial oxidation of polyethylene glycol.  |  Kawai, F., et al. 1978. Appl Environ Microbiol. 35: 679-84. PMID: 646355
  15. Subacute oral toxicity of tetraethylene glycol and ethylene glycol administered to Wistar rats.  |  Schladt, L., et al. 1998. Exp Toxicol Pathol. 50: 257-65. PMID: 9681658

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetraethylene glycol, 500 ml

sc-272567
500 ml
$44.00