Date published: 2026-5-8

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Tetraethylammonium fluoride dihydrate (CAS 665-46-3)

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Alternate Names:
N,N,N-TRIETHYL-ETHANAMINIUFLUORIDE
Application:
Tetraethylammonium fluoride dihydrate is a quaternary ammonium salt
CAS Number:
665-46-3
Molecular Weight:
185.28
Molecular Formula:
C8H20NF•2H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetraethylammonium fluoride dihydrate is a compound that functions as a quaternary ammonium salt. It acts as a phase-transfer catalyst, facilitating the transfer of a fluoride anion from an aqueous phase to an organic phase. Tetraethylammonium Fluoride Dihydrate′s mechanism of action involves the formation of a complex with the fluoride anion, allowing it to be transported across the phase boundary. In this way, it enables the introduction of fluoride into organic reactions that typically occur in non-aqueous solvents. The compound′s ability to facilitate the transfer of fluoride ions is particularly useful in organic synthesis, where the presence of fluoride is required for specific reactions. By serving as a phase-transfer catalyst, tetraethylammonium fluoride dihydrate plays a role in enabling the execution of various organic transformations that necessitate the use of fluoride ions.


Tetraethylammonium fluoride dihydrate (CAS 665-46-3) References

  1. Hydrogen bonding Part 46. Thermodynamic and IR study of stability and structure of tetraethylammonium fluoride·2.75H2O, tetraethylammonium fluoride·2.00H2O, tetramethylammonium fluoride·3.00H2O, and tetraethylammonium fluoride·5.00H2O  |  Kenneth M. Harmon, Barbara A. Southworth, Jennifer Harmon. 1993. Journal of Molecular Structure. 300: 339-349.
  2. Fluoride-ion deboronation of p-fluorophenyl-ortho- and -meta-carboranes. NMR evidence for the new fluoroborate, HOBHF2−  |  Mark A. Fox, J.A.Hugh MacBride, Kenneth Wade. 1997. Polyhedron. 16: 2499-2507.
  3. The Cubic Superstructure-I of Tetrabutylammonium Fluoride (C4H9)4NF·29.7H2O Clathrate Hydrate  |  V. Yu. Komarov, T. V. Rodionova, I. S. Terekhova & N. V. Kuratieva. 2007. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 59: 11–15.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetraethylammonium fluoride dihydrate, 5 g

sc-253667
5 g
$36.00