Date published: 2025-10-20

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Tetradecanoyl-L-homoserine lactone (CAS 202284-87-5)

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Alternate Names:
N-[(3S)-tetrahydro-2-oxo-3-furanyl]-tetradecanamide
Application:
Tetradecanoyl-L-homoserine lactone is a major modulator for cell communication
CAS Number:
202284-87-5
Purity:
≥99%
Molecular Weight:
311.50
Molecular Formula:
C18H33NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetradecanoyl-L-homoserine lactone is a quorum sensing molecule, which is secreted by bacteria in order to communicate with other bacteria in their environment. It allows bacteria to coordinate their activities in response to changes in their environment. It is one of the major chemical modulators of within and between cell communication and regulation. This chemical is useful for studying Quorum sensing in vitro. Specifically, it is employed to investigate bacterial gene expression, physiology, metabolism, biofilm formation, and pathogenesis.


Tetradecanoyl-L-homoserine lactone (CAS 202284-87-5) References

  1. Quantification of Proteus mirabilis virulence factors and modulation by acylated homoserine lactones.  |  Stankowska, D., et al. 2008. J Microbiol Immunol Infect. 41: 243-53. PMID: 18629420
  2. Simultaneous quantitative profiling of N-acyl-L-homoserine lactone and 2-alkyl-4(1H)-quinolone families of quorum-sensing signaling molecules using LC-MS/MS.  |  Ortori, CA., et al. 2011. Anal Bioanal Chem. 399: 839-50. PMID: 21046079
  3. The impact of quorum sensing on the virulence of Aeromonas hydrophila and Aeromonas salmonicida towards burbot (Lota lota L.) larvae.  |  Natrah, FM., et al. 2012. Vet Microbiol. 159: 77-82. PMID: 22465799
  4. Short chain N-acyl homoserine lactone production by soil isolate Burkholderia sp. strain A9.  |  Chen, JW., et al. 2013. Sensors (Basel). 13: 13217-27. PMID: 24084115
  5. The involvement of bacterial quorum sensing in the spoilage of refrigerated Litopenaeus vannamei.  |  Zhu, S., et al. 2015. Int J Food Microbiol. 192: 26-33. PMID: 25305441
  6. Biofilm Formation and Quorum-Sensing-Molecule Production by Clinical Isolates of Serratia liquefaciens.  |  Remuzgo-Martínez, S., et al. 2015. Appl Environ Microbiol. 81: 3306-15. PMID: 25746999
  7. Enhanced system performance by dosing ferroferric oxide during the anaerobic treatment of tryptone-based high-strength wastewater.  |  Yin, Q., et al. 2017. Appl Microbiol Biotechnol. 101: 3929-3939. PMID: 28235990
  8. Characterization of quorum sensing genes and N-acyl homoserine lactones in Citrobacter amalonaticus strain YG6.  |  Kher, HL., et al. 2019. Gene. 684: 58-69. PMID: 30321658
  9. AhlX, an N-acylhomoserine Lactonase with Unique Properties.  |  Liu, P., et al. 2019. Mar Drugs. 17: PMID: 31261836
  10. Acyl homoserine lactone-mediated quorum sensing in the oral cavity: a paradigm revisited.  |  Muras, A., et al. 2020. Sci Rep. 10: 9800. PMID: 32555242
  11. Exogenous N-hexanoyl-L-homoserine lactone assists in upflow anaerobic sludge blanket recovery from acetate accumulation via aceticlastic methanogens enrichment.  |  Zhang, Y., et al. 2022. Bioresour Technol. 346: 126600. PMID: 34973403
  12. Quorum-sensing molecules: Sampling, identification and characterization of N-acyl-homoserine lactone in Vibrio sp.  |  Laj, N., et al. 2022. Saudi J Biol Sci. 29: 2733-2737. PMID: 35531216
  13. Transboundary intercellular communications between Penicillium and bacterial communities during sludge bulking: Inspirations on quenching fungal dominance.  |  Feng, Z., et al. 2022. Water Res. 221: 118829. PMID: 35839592

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetradecanoyl-L-homoserine lactone, 5 mg

sc-391648
5 mg
$64.00