Date published: 2025-10-8

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Tetrachloroethylene (CAS 127-18-4)

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Alternate Names:
Perchloroethylene
CAS Number:
127-18-4
Molecular Weight:
165.83
Molecular Formula:
C2Cl4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetrachloroethylene, known as perchloroethylene or PCE, serves as a volatile organic compound (VOC) with widespread utility in diverse industrial and commercial processes. It plays a central role in the synthesis of various compounds, spanning agrochemicals and polymers. Furthermore, it serves as an essential component in sample preparation for analytical methods like chromatography and spectroscopy. Additionally, tetrachloroethylene functions as a versatile solvent, finding application in numerous reactions, including polymer synthesis, organometallic compound preparation, and natural product extraction.


Tetrachloroethylene (CAS 127-18-4) References

  1. Tetrachloroethylene emissions and exposure in dry cleaning.  |  Räisänen, J., et al. 2001. J Air Waste Manag Assoc. 51: 1671-5. PMID: 15666472
  2. Systematic literature review of uses and levels of occupational exposure to tetrachloroethylene.  |  Gold, LS., et al. 2008. J Occup Environ Hyg. 5: 807-39. PMID: 18949603
  3. Early lifestage exposure and potential developmental susceptibility to tetrachloroethylene.  |  Brown Dzubow, R., et al. 2010. Birth Defects Res B Dev Reprod Toxicol. 89: 50-65. PMID: 20041493
  4. Residual tetrachloroethylene in dry-cleaned clothes.  |  Kawauchi, T. and Nishiyama, K. 1989. Environ Res. 48: 296-301. PMID: 2924758
  5. Enhanced removal of tetrachloroethylene from aqueous solutions by biodegradation coupled with nZVI modified by layered double hydroxide.  |  Wang, Q., et al. 2020. Chemosphere. 243: 125260. PMID: 31734600
  6. A pilot study characterizing tetrachloroethylene exposure with exhaled breath in an impacted community.  |  Liu, S., et al. 2022. Environ Pollut. 297: 118756. PMID: 34968620
  7. Physisorption of trichloroethylene and tetrachloroethylene on novel zeta arsenene nanotubes - A first-principles study.  |  Jyothi, MS., et al. 2022. J Mol Graph Model. 115: 108233. PMID: 35661590
  8. Expanding the calibration range of compound-specific chlorine isotope analysis by the preparation of a 37 Cl-enriched tetrachloroethylene.  |  Buchner, D., et al. 2022. Rapid Commun Mass Spectrom. 36: e9378. PMID: 35975721
  9. Acute tetrachloroethylene fatality.  |  Lukaszewski, T. 1979. Clin Toxicol. 15: 411-5. PMID: 540489
  10. Biological actions and interactions of tetrachloroethylene.  |  Reichert, D. 1983. Mutat Res. 123: 411-29. PMID: 6358882
  11. A tetrachloroethylene fatality.  |  Levine, B., et al. 1981. J Forensic Sci. 26: 206-9. PMID: 7205186
  12. Population toxicokinetics of tetrachloroethylene.  |  Bois, FY., et al. 1996. Arch Toxicol. 70: 347-55. PMID: 8975633
  13. Categorical regression analysis of acute exposure to tetrachloroethylene.  |  Guth, DJ., et al. 1997. Risk Anal. 17: 321-32. PMID: 9232016

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetrachloroethylene, 1 L

sc-237025
1 L
$116.00