Date published: 2025-12-2

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Tetrabutylammonium fluoride trihydrate (CAS 87749-50-6)

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Application:
Tetrabutylammonium fluoride trihydrate is a biochemical for the preparation of deprotecting agents in the preparation of cellulose derivatives, synthesis of lipophilic peptides for DNA transfections in vivo, and dehydrobromination reactions
CAS Number:
87749-50-6
Molecular Weight:
315.51
Molecular Formula:
C16H36FN•3H2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetrabutylammonium fluoride trihydrate is a employed salt within the realms of organic chemistry and biochemistry. This compound serves as a potent base, finding extensive use in diverse applications, including organic compound synthesis, buffer preparation, and protein purification. Tetrabutylammonium fluoride trihydrate holds significant importance in both organic chemistry and biochemistry. It plays a pivotal role in the synthesis of various organic compounds, such as carboxylic acids, amines, and alcohols. Additionally, it facilitates the purification of nucleic acids, including DNA and RNA. Acting as a strong base, tetrabutylammonium fluoride trihydrate possesses the ability to deprotonate a wide range of organic compounds.


Tetrabutylammonium fluoride trihydrate (CAS 87749-50-6) References

  1. Exploitation of reactivity and selectivity in cellulose functionalization using unconventional media for the design of products showing new superstructures.  |  Liebert, TF. and Heinze, TJ. 2001. Biomacromolecules. 2: 1124-32. PMID: 11777383
  2. A neutral organometallic fluoro complex can be a good ligand.  |  Coue, L., et al. 2004. Chemistry. 10: 1906-12. PMID: 15079829
  3. Studies on the homogeneous acetylation of cellulose in the novel solvent dimethyl sulfoxide/tetrabutylammonium fluoride trihydrate.  |  Ass, BA., et al. 2004. Macromol Biosci. 4: 1008-13. PMID: 15529395
  4. Ionic liquids as reaction medium in cellulose functionalization.  |  Heinze, T., et al. 2005. Macromol Biosci. 5: 520-5. PMID: 15948229
  5. Water-soluble 3-O-(2-methoxyethyl)cellulose: synthesis and characterization.  |  Heinze, T. and Koschella, A. 2008. Carbohydr Res. 343: 668-73. PMID: 18261718
  6. Synthesis of alkynes from vinyl triflates using tetrabutylammonium fluoride.  |  Okutani, M. and Mori, Y. 2015. Chem Pharm Bull (Tokyo). 63: 393-6. PMID: 25948333

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetrabutylammonium fluoride trihydrate, 10 g

sc-251155
10 g
$57.00

Tetrabutylammonium fluoride trihydrate, 50 g

sc-251155A
50 g
$203.00