Date published: 2026-6-9

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Tetrabromothiophene (CAS 3958-03-0)

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Alternate Names:
Perbromothiophene
CAS Number:
3958-03-0
Molecular Weight:
399.72
Molecular Formula:
C4Br4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetrabromothiophene is a crystalline substance, insoluble in water but dissolves in many organic solvents. It′s notably reactive, participating in several reactions like halogenation, oxidation, and reduction. Its applications span across research and industry, particularly in organic electronics and optoelectronics. Tetrabromothiophene acts as a precursor to other brominated entities. Given its significant bromine content, it′s also used as a flame retardant.


Tetrabromothiophene (CAS 3958-03-0) References

  1. Structures of tetrabromothiophene and tetrabromoselenophene: the influence of the heteroatom on the heterophene packing.  |  Helmholdt, RB., et al. 2007. Acta Crystallogr B. 63: 783-90. PMID: 17873447
  2. Selective mono- to perarylations of tetrabromothiophene by a cyclobutene-1,2-diylbisimidazolium preligand.  |  Rahimi, A., et al. 2011. J Org Chem. 76: 7316-25. PMID: 21842887
  3. Efficient synthesis of thieno[3,2-b:4,5-b']diindoles and benzothieno[3,2-b]indoles by Pd-catalyzed site-selective C-C and C-N coupling reactions.  |  Hung, TQ., et al. 2012. Org Biomol Chem. 10: 9041-4. PMID: 23073643
  4. Selective C-arylation of 2,5-dibromo-3-hexylthiophene via Suzuki cross coupling reaction and their pharmacological aspects.  |  Ikram, HM., et al. 2015. Molecules. 20: 5202-14. PMID: 25806546
  5. Synthesis and properties of mono- and dimetal Fischer multicarbene complexes derived from thiophene and thieno[2,3-b]thiophene.  |  Lamprecht, Z., et al. 2015. Dalton Trans. 44: 19218-31. PMID: 26488538
  6. One Pot Selective Arylation of 2-Bromo-5-Chloro Thiophene; Molecular Structure Investigation via Density Functional Theory (DFT), X-ray Analysis, and Their Biological Activities.  |  Rasool, N., et al. 2016. Int J Mol Sci. 17: PMID: 27367666
  7. Pd-Catalyzed one-pot sequential cross-coupling reactions of tetrabromothiophene.  |  Saini, KM., et al. 2017. Org Biomol Chem. 15: 10289-10298. PMID: 29188248
  8. A Chalcogen-Bonding Cascade Switch for Planarizable Push-Pull Probes.  |  Macchione, M., et al. 2019. Angew Chem Int Ed Engl. 58: 15752-15756. PMID: 31539191
  9. Methyl Scanning for Mechanochemical Chalcogen-Bonding Cascade Switches.  |  Zhang, X., et al. 2020. ChemistryOpen. 9: 18-22. PMID: 31921541
  10. Photodissociation dynamics of halogenated aromatic molecules: the case of core-ionized tetrabromothiophene.  |  Pihlava, L., et al. 2021. Phys Chem Chem Phys. 23: 21249-21261. PMID: 34542547
  11. First-principles study of structural, elastic and electronic properties of naphyne and naphdiyne.  |  Liu, C., et al. 2020. RSC Adv. 10: 35349-35355. PMID: 35515647
  12. An Ultrastable Porous Polyhedral Oligomeric Silsesquioxane/Tetraphenylthiophene Hybrid as a High-Performance Electrode for Supercapacitors.  |  Ejaz, M., et al. 2022. Molecules. 27: PMID: 36234775
  13. Important Requirements for Desorption/Ionization Mass Spectrometric Measurements of Temozolomide-Induced 2'-Deoxyguanosine Methylations in DNA.  |  Fresnais, M., et al. 2023. Cancers (Basel). 15: PMID: 36765673

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetrabromothiophene, 25 g

sc-237010
25 g
$56.00