Date published: 2025-10-6

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Tetrabromomethane (CAS 558-13-4)

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Alternate Names:
Carbon tetrabromide
CAS Number:
558-13-4
Molecular Weight:
331.63
Molecular Formula:
CBr4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetrabromomethane, a halogenated hydrocarbon, finds applications in organic synthesis and spectroscopy. It serves as a versatile reagent in the synthesis of diverse organic compounds, encompassing alkenes, alcohols, and amines. It plays a role in the production of brominated derivatives, including brominated hydrocarbons, ethers, and esters. In spectroscopy, tetrabromomethane is employed to ascertain the structure and composition of organic compounds, while in chromatography, it facilitates the separation of compounds within a mixture.


Tetrabromomethane (CAS 558-13-4) References

  1. Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.  |  Wnuk, SF., et al. 2000. J Med Chem. 43: 1180-6. PMID: 10737751
  2. Photochemical reaction pathways of carbon tetrabromide in solution probed by picosecond X-ray diffraction.  |  Kong, Q., et al. 2007. J Am Chem Soc. 129: 13584-91. PMID: 17939658
  3. Mild one-step synthesis of dibromo compounds from cyclic ethers.  |  Billing, P. and Brinker, UH. 2012. J Org Chem. 77: 11227-31. PMID: 23151041
  4. Organocatalyzed direct glycosylation of unprotected and unactivated carbohydrates.  |  Schmalisch, S. and Mahrwald, R. 2013. Org Lett. 15: 5854-7. PMID: 24180643
  5. Light-enabled synthesis of anhydrides and amides.  |  McCallum, T. and Barriault, L. 2015. J Org Chem. 80: 2874-8. PMID: 25689228
  6. Double Ring Expansion from an Aromatic [18]Porphyrin(1.1.1.1) to an Antiaromatic [20]Porphyrin(2.1.2.1).  |  Umetani, M., et al. 2016. Angew Chem Int Ed Engl. 55: 8095-9. PMID: 27194115
  7. Ruthenium-Catalyzed meta-Carboxylation.  |  Barlow, HL., et al. 2017. Org Lett. 19: 6662-6665. PMID: 29182341
  8. An efficient synthesis of benzothiazole using tetrabromomethane as a halogen bond donor catalyst.  |  Kazi, I. and Sekar, G. 2019. Org Biomol Chem. 17: 9743-9756. PMID: 31696198
  9. Influence of Acrylic Acid on Kinetics of UV-Induced Cotelomerization Process and Properties of Obtained Pressure-Sensitive Adhesives.  |  Kowalczyk, A., et al. 2020. Materials (Basel). 13: PMID: 33322468
  10. The Effect of Type-I Photoinitiators on the Kinetics of the UV-Induced Cotelomerization Process of Acrylate Monomers and Properties of Obtained Pressure-Sensitive Adhesives.  |  Kowalczyk, A., et al. 2021. Materials (Basel). 14: PMID: 34443085
  11. Chromium carbides and cyclopropenylidenes.  |  Kurogi, T., et al. 2021. Chem Sci. 12: 14281-14287. PMID: 34760214
  12. Access to gem-Dibromoenones Enabled by Carbon-Centered Radical Addition to Terminal Alkynes in Water Solution.  |  Zeng, X., et al. 2021. Org Lett. 23: 9058-9062. PMID: 34766780
  13. Visible light-driven carbamoyloxylation of the α-C(sp3)-H bond of arylacetones via radical-initiated hydrogen atom transfer.  |  He, X., et al. 2022. Chem Commun (Camb). 58: 5845-5848. PMID: 35466975
  14. CBr4 catalyzed activation of α,β-unsaturated ketones.  |  Bera, SK., et al. 2022. Org Biomol Chem. 20: 7085-7091. PMID: 36039810
  15. Bottom-Up Synthesis of Metalated Carbyne Ribbons via Elimination Reactions.  |  Gao, W., et al. 2023. J Am Chem Soc. 145: 6203-6209. PMID: 36897772

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetrabromomethane, 5 g

sc-251148
5 g
$30.00

Tetrabromomethane, 100 g

sc-251148A
100 g
$63.00

Tetrabromomethane, 500 g

sc-251148B
500 g
$267.00