Testosterone Antibody (XM209): sc-52242

Testosterone Antibody (XM209) is a mouse monoclonal IgG2a antibody that detects the Testosterone protein of mouse, rat, and human origin by enzyme-linked immunosorbent assay (ELISA). Anti-Testosterone antibody (XM209) is available as the non-conjugated form. Testosterone is a steroid hormone from the androgen group, primarily secreted by the testis, with smaller amounts produced in the ovaries, adrenal glands, and placenta, typically derived from cholesterol. This hormone plays a crucial role in male sexual development, particularly during fetal growth, as Testosterone is essential for the formation of male external genitalia. Beyond developmental functions, Testosterone stimulates protein synthesis, which contributes to increased muscular development observed in males. Additionally, Testosterone is responsible for the emergence of secondary sexual characteristics, such as facial hair and deeper voice, during puberty. Testosterone influences health and well-being in both males and females, affecting mood, energy levels, and overall physical health. Certain synthetic derivatives of Testosterone are utilized in medical treatments, particularly for advanced disseminated breast cancer in women, especially when the disease has metastasized to the bones, highlighting the hormone′s significance beyond traditional roles.

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Testosterone Antibody (XM209) References:

1. The effects of exogenous testosterone on sexuality and mood of normal men.  |  Anderson, RA., et al. 1992. J Clin Endocrinol Metab. 75: 1503-7. PMID: 1464655
2. In men older than 70 years, total testosterone remains stable while free testosterone declines with age. The Health in Men Study.  |  Yeap, BB., et al. 2007. Eur J Endocrinol. 156: 585-94. PMID: 17468195
3. Randomized controlled trial to evaluate transdermal testosterone in female cancer survivors with decreased libido; North Central Cancer Treatment Group protocol N02C3.  |  Barton, DL., et al. 2007. J Natl Cancer Inst. 99: 672-9. PMID: 17470735
4. The development of a radioimmunoassay system for testosterone (T) and dihydrotestosterone (DHT). Part 1. The preparation of the T-derivatives and T-protein conjugates.  |  Neacşu, E., et al. 1990. Endocrinologie. 28: 25-31. PMID: 2080417
5. Psychological and behavioural effects of endogenous testosterone levels and anabolic-androgenic steroids among males. A review.  |  Bahrke, MS., et al. 1990. Sports Med. 10: 303-37. PMID: 2263798
6. Anabolic steroids: a review of the literature.  |  Haupt, HA. and Rovere, GD. 1984. Am J Sports Med. 12: 469-84. PMID: 6391216
7. Characterisation of monoclonal antibodies raised against testosterone.  |  Fantl, VE. and Wang, DY. 1983. J Steroid Biochem. 19: 1605-10. PMID: 6645496
8. Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis.  |  Urban, RJ., et al. 1995. Am J Physiol. 269: E820-6. PMID: 7491931
9. Effects of testosterone replacement therapy in old hypogonadal males: a preliminary study.  |  Morley, JE., et al. 1993. J Am Geriatr Soc. 41: 149-52. PMID: 8426037

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Testosterone Antibody (XM209) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Testosterone Antibody (XM209) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Testosterone Antibody (XM209) Specifications

Alternate Product Name: Testosterone

Product Clone Name: XM209

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Testosterone

Epitope Species: human

Product Reactivity/Detection: Testosterone

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Testosterone Antibody (XM209): N/A