TES, sodium salt (CAS 70331-82-7)

TES sodium salt, or N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid sodium salt, is a zwitterionic buffer widely used in biochemical and biological research for its effective pH stabilization capabilities in the range of 6.8 to 8.2. This buffer excels at maintaining stable pH levels by absorbing or releasing hydrogen ions, which is critical for maintaining the activity of enzymes and other sensitive biomolecules during experiments. TES sodium salt is particularly valuable in cell culture applications, where it helps maintain an optimal ionic environment that promotes cellular health and proliferation without significant interference. Additionally, its use extends to protein purification, where it preserves the native state of proteins, and in electrophoresis media preparation, where its low ionic strength and minimal metal ion interaction are beneficial. The buffer is also favored in spectrophotometric assays due to its low UV absorbance, ensuring that it does not interfere with optical measurements. This combination of properties makes TES sodium salt a versatile and indispensable tool in laboratories, supporting a wide array of scientific studies by ensuring precise pH control and minimal interference with biological processes.