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TES, Free Acid (CAS 7365-44-8)

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Alternate Names:
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid
Application:
TES, Free Acid is N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid, a structural analog to Tris buffer
CAS Number:
7365-44-8
Purity:
≥99%
Molecular Weight:
229.25
Molecular Formula:
C6H15NO6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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TES, Free Acid is a structural analog to Tris buffer. It is one of the ethanesulfonic acid series of biological buffers developed by Good et al. Good′s buffer criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pKa with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range, and easily synthesized. TES probably exists in solution as a zwitterion. Because the pKa is 7.4 (physiological pH) this buffer has considerable potential for a variety of biological applications. A buffer using TES free acid can be prepared by titrating the free acid (sc-206102) with sodium hydroxide to the desired pH, using about a half-equivalent of NaOH. Alternatively, solutions of equimolar TES free acid and TES sodium (sc-264384) can be mixed to attain a buffer of the desired pH.


TES, Free Acid (CAS 7365-44-8) References

  1. Effect of carbonylcyanide m-chlorophenylhydrazone on the calcium-stimulated ATPase activity of erythrocyteghosts.  |  Hayashi, H., et al. 1975. Biochim Biophys Acta. 394: 144-55. PMID: 124597
  2. Cryopreservation of epididymal sperm collected postmortem in the Tasmanian devil (Sarcophilus harrisii).  |  Keeley, T., et al. 2012. Theriogenology. 78: 315-25. PMID: 22444554
  3. On the use of 31P NMR for the quantification of hydrosoluble phosphorus-containing compounds in coral host tissues and cultured zooxanthellae.  |  Godinot, C., et al. 2016. Sci Rep. 6: 21760. PMID: 26902733
  4. Proprioceptive Opsin Functions in Drosophila Larval Locomotion.  |  Zanini, D., et al. 2018. Neuron. 98: 67-74.e4. PMID: 29551493
  5. Sensorimotor pathway controlling stopping behavior during chemotaxis in the Drosophila melanogaster larva.  |  Tastekin, I., et al. 2018. Elife. 7: PMID: 30465650
  6. Chromophore-Independent Roles of Opsin Apoproteins in Drosophila Mechanoreceptors.  |  Katana, R., et al. 2019. Curr Biol. 29: 2961-2969.e4. PMID: 31447373
  7. Mushroom Bodies Are Required for Learned Visual Navigation, but Not for Innate Visual Behavior, in Ants.  |  Buehlmann, C., et al. 2020. Curr Biol. 30: 3438-3443.e2. PMID: 32707069
  8. Hydrogen ion buffers for biological research.  |  Good, NE., et al. 1966. Biochemistry. 5: 467-77. PMID: 5942950
  9. Spectrin phosphorylation and shape change of human erythrocyte ghosts.  |  Patel, VP. and Fairbanks, G. 1981. J Cell Biol. 88: 430-40. PMID: 7204501
  10. Yeast mitochondrial F1-ATPase--effects of metal ions.  |  Jenkins, WT. 1994. Arch Biochem Biophys. 313: 89-95. PMID: 8053693

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

TES, Free Acid, 25 g

sc-216102B
25 g
$56.00

TES, Free Acid, 100 g

sc-216102
100 g
$112.00

TES, Free Acid, 250 g

sc-216102C
250 g
$194.00

TES, Free Acid, 1 kg

sc-216102A
1 kg
$717.00

TES, Free Acid, 2.5 kg

sc-216102D
2.5 kg
$1617.00

TES, Free Acid, 10 kg

sc-216102E
10 kg
$5528.00

TES, Free Acid, 50 kg

sc-216102F
50 kg
$24490.00