Date published: 2025-10-27

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tert-Butyl peroxide (CAS 110-05-4)

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Alternate Names:
Di-tert-butyl Peroxide
CAS Number:
110-05-4
Molecular Weight:
146.23
Molecular Formula:
C8H18O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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tert-Butyl peroxide (DTBP) is a colorless, volatile liquid characterized by its sweet odor. With the chemical formula C8H18O2, it serves as an organic peroxide compound. tert-Butyl peroxide finds extensive applications in both research and industry. It plays a role as an initiator in polymerization reactions and acts as a catalyst for organic synthesis. Furthermore, it contributes to the production of polymers and various materials, acting as a cross-linker in the synthesis of polyolefins.


tert-Butyl peroxide (CAS 110-05-4) References

  1. The mechanism of catalytic methylation of 2-phenylpyridine using di-tert-butyl peroxide.  |  Sharma, AK., et al. 2014. Dalton Trans. 43: 10183-201. PMID: 24875675
  2. Di-tert-butyl peroxide-promoted α-alkylation of α-amino carbonyl compounds by simple alkanes.  |  Peng, H., et al. 2014. J Org Chem. 79: 9847-53. PMID: 25243610
  3. Metal-Free Preparation of Cycloalkyl Aryl Sulfides via Di-tert-butyl Peroxide-Promoted Oxidative C(sp3)[BOND]H Bond Thiolation of Cycloalkanes.  |  Zhao, J., et al. 2014. Adv Synth Catal. 356: 2719-2724. PMID: 25505857
  4. One-Pot Synthesis of 2,5-Diaryl 1,3,4-Oxadiazoles via Di-tert-butyl Peroxide Promoted N-Acylation of Aryl Tetrazoles with Aldehydes.  |  Wang, L., et al. 2015. J Org Chem. 80: 4743-8. PMID: 25860162
  5. Di-tert-butyl peroxide-mediated atom-transfer radical addition of 2-chlorodithiane to aryl alkynes under mild conditions.  |  Lai, J., et al. 2015. Chemistry. 21: 14328-31. PMID: 26296151
  6. Copper-catalyzed N-methylation/ethylation of sulfoximines.  |  Teng, F., et al. 2015. Org Biomol Chem. 13: 9934-7. PMID: 26332754
  7. Combined Di-tert-butyl Peroxide and Inorganic Base Promoted α-Alkylation of Ethers with Arenesulfonylindoles.  |  Gu, Z., et al. 2017. J Org Chem. 82: 5441-5448. PMID: 28471176
  8. Cascade Reaction of Propargyl Amines with AgSCF3, as Well as One-Pot Reaction of Propargyl Amines, AgSCF3, and Di- tert-butyl Peroxide: Access to Allenyl Thiocyanates and Allenyl Trifluoromethylthioethers.  |  Zhen, L., et al. 2018. Org Lett. 20: 3109-3113. PMID: 29745677
  9. Di-tert-butyl Peroxide-Mediated Radical C(sp2/sp3)-S Bond Cleavage and Group-Transfer Cyclization.  |  Luo, K., et al. 2019. Org Lett. 21: 7851-7856. PMID: 31524412
  10. tert-Butyl peroxide (TBHP)/KI-mediated dual C(sp2)-H bond amination of arylamines with α-diazo carbonyls toward 1,2,4-benzotriazines.  |  Zhang, TS., et al. 2019. Chem Commun (Camb). 55: 13231-13234. PMID: 31631212
  11. Di-tert-butyl Peroxide (DTBP)-Mediated Oxysilylation of Unsaturated Carboxylic Acids for the Synthesis of Silyl Lactones.  |  Nozawa-Kumada, K., et al. 2020. Org Lett. 22: 9591-9596. PMID: 33269934
  12. Photo-induced metal-free dehydrogenative N-N homo-coupling.  |  Balakrishna, B., et al. 2022. Chem Commun (Camb). 58: 10977-10980. PMID: 36093722
  13. Optimization of Bauhinia parviflora biodiesel production for higher yield and its compatibility assessment with water and Di-tert-butyl peroxide emulsion.  |  Vellaiyan, S., et al. 2023. Waste Manag. 162: 63-71. PMID: 36948114

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Butyl peroxide, 5 ml

sc-224299
5 ml
$45.00

tert-Butyl peroxide, 250 ml

sc-224299A
250 ml
$72.00