Date published: 2025-12-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

tert-Butyl Isopropyl Ether (CAS 17348-59-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
2-Methyl-2-(1-methylethoxy)propane; 2-Isopropoxy-2-methylpropane; Isopropyl tert-Butyl Ether
CAS Number:
17348-59-3
Molecular Weight:
116.2
Molecular Formula:
C7H16O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

tert-Butyl isopropyl ether is a chemical compound utilized in the field of organic chemistry, primarily as a solvent or as an intermediate in the synthesis of more complex organic molecules. Its structure, characterized by the presence of both tert-butyl and isopropyl groups, makes it an interesting subject of study in terms of steric effects on reactivity and solvation. Researchers use tert-Butyl isopropyl ether to probe the properties of ethers in facilitating various organic reactions, particularly those that are sensitive to the presence of water or require anhydrous conditions. The compound is also used in the examination of phase behavior in mixed solvent systems and can be a component in the study of non-covalent interactions between solute and solvent molecules. In addition, its application in the preparation of organometallic reagents is noteworthy, as it can influence reaction pathways and product selectivity due to its unique structural attributes.


tert-Butyl Isopropyl Ether (CAS 17348-59-3) References

  1. Rapid method for determination of residual tert-butanol in liposomes using solid-phase microextraction and gas chromatography.  |  Sullivan, JC., et al. 2010. J Chromatogr Sci. 48: 289-93. PMID: 20412651
  2. Heats of formation of organic compounds by a simple calculation.  |  Zavitsas, AA., et al. 2010. J Org Chem. 75: 6502-15. PMID: 20825149
  3. Group additivity values for estimating the enthalpy of formation of organic compounds: an update and reappraisal. 1. C, H, and O.  |  Holmes, JL. and Aubry, C. 2011. J Phys Chem A. 115: 10576-86. PMID: 21882846
  4. Hydrogen atom reactivity toward aqueous tert-butyl alcohol.  |  Lymar, SV. and Schwarz, HA. 2012. J Phys Chem A. 116: 1383-9. PMID: 22229877
  5. Lightsticks content toxicity: effects of the water soluble fraction on the oyster embryonic development.  |  de Araujo, MM., et al. 2015. Chemosphere. 139: 73-80. PMID: 26070145
  6. Contaminants migrating from crossed-linked polyethylene pipes and their effect on drinking water odour.  |  Kalweit, C., et al. 2019. Water Res. 161: 341-353. PMID: 31212240
  7. RespiraTox - Development of a QSAR model to predict human respiratory irritants.  |  Wehr, MM., et al. 2022. Regul Toxicol Pharmacol. 128: 105089. PMID: 34861320
  8. Dependence of the protonation constants of organic compounds on their molecular volume  |  , et al. (2007). Russian Journal of General Chemistry. volume 77,: pages 234–240.
  9. Use of a neural network to determine the normal boiling points of acyclic ethers, peroxides, acetals and their sulfur analogues  |  Driss Cherqaoui, Didier Villemin, Abdelhalim Mesbah, Jean-Michel Cense and Vladimir Kvasnicka. 1994. J. Chem. Soc., Faraday Trans.,.,90,: 2015-2019.
  10. A Comparative Thermodynamic and Kinetic Study of the Reaction between Olefins and Light Alcohols Leading to Branched Ethers. Reaction Calorimetry Study of the Formation of tert-Amyl Methyl Ether (TAME) and tert-Butyl Isopropyl Ether (IPTBE)  |  Lluís Solà, Miquel A. Pericàs, Fidel Cunill, and J. Felipe Izquierdo. 1997. Ind. Eng. Chem. Res., 36, 6,: 2012–2018.
  11. Equilibrium Constants for the Liquid-Phase Synthesis of Isopropyl tert-Butyl Ether from 2-Propanol and Isobutene  |  Adela Calderón, Javier Tejero, José Felipe Izquierdo, Montserrat Iborra, and Fidel Cunill. 1997,. Ind. Eng. Chem. Res. 36, 3:, 896–902.
  12. An Extended Istomin-Palm Model for Estimating the Enthalpies of Formation of the Two-Direction Extending Compounds R1-Y-R2  |  CAO, Chen-Zhong; WU, Ya-Xin. 15 January 2013. Acta Physico-Chimica Sinica,. Volume 29, Number 1,:, pp. 35-42(8).

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Butyl Isopropyl Ether, 100 mg

sc-504468
100 mg
$372.00

tert-Butyl Isopropyl Ether, 500 mg

sc-504468A
500 mg
$1107.00