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tert-Butyl hydroperoxide solution (CAS 75-91-2)

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Alternate Names:
1,1-Dimethylethyl hydroperoxide
CAS Number:
75-91-2
Molecular Weight:
90.12
Molecular Formula:
C4H10O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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tert-Butyl hydroperoxide solution is a clear liquid organic peroxide, used in various chemical synthesis and industrial applications. tert-Butyl hydroperoxide serves as an initiator for polymerization reactions, a key reagent in the oxidation of organic compounds, and is involved in the synthesis of epoxides, alcohols, and ketones through various oxidative processes. In chemical synthesis, tert-Butyl hydroperoxide′s role as an oxidizing agent is critical for introducing oxygen into organic substrates, facilitating the transformation of hydrocarbons into more functionalized molecules. This capability makes it useful in the production of fine chemicals, where precise and controlled oxidation is necessary. Its use in the synthesis of epoxides, for example, is essential in creating building blocks for a wide range of synthetic applications, including the production of plastics and agrochemicals. tert-Butyl hydroperoxide is also employed in the oxidative desulfurization of fuels, a process critical for reducing sulfur content and improving fuel quality. This application is particularly important in the context of environmental regulations aiming to reduce air pollution from combustion engines.


tert-Butyl hydroperoxide solution (CAS 75-91-2) References

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  2. (R)-(+)-2,2'-Bis(diphenylphosphinoyl)-1,1'-binaphthyl.  |  Bunten, KA., et al. 2000. Acta Crystallogr C. 56: E267. PMID: 15263123
  3. The influence of the solvent on the epoxidation of cis,trans,trans-1,5,9-cyclododecatriene to trans-1,2-epoxy-cis,trans-5,9-cyclododecadiene by catalytic system tert-butyl hydroperoxide/Mo(CO)6.  |  Lewandowski, G., et al. 2005. J Hazard Mater. 120: 45-50. PMID: 15811663
  4. Effect of vitamin C, deferoxamine, quercetin and rutin against tert-butyl hydroperoxide oxidative damage in human erythrocytes.  |  Krukoski, DW., et al. 2009. Hematology. 14: 168-72. PMID: 19490763
  5. Effect of thiol drugs on tert-butyl hydroperoxide induced luminol chemiluminescence in human erythrocytes, erythrocyte lysate, and erythrocyte membranes.  |  Sajewicz, W. 2010. Chem Biol Interact. 186: 144-51. PMID: 20430017
  6. Identification of mercury methylation product by tert-butyl compounds in aqueous solution under light irradiation.  |  Chen, B., et al. 2015. Mar Pollut Bull. 98: 40-6. PMID: 26165936
  7. One-Pot Magnetic Iron Oxide-Carbon Nanodot Composite-Catalyzed Cyclooxidative Aqueous Tandem Synthesis of Quinazolinones in the Presence of tert-Butyl Hydroperoxide.  |  Majumdar, B., et al. 2018. ACS Omega. 3: 13711-13719. PMID: 31458072
  8. Combination of tert-butyl hydroperoxide with vorinostat induces cell death of Acanthamoeba through cell cycle arrest.  |  Lee, HA., et al. 2020. Exp Parasitol. 210: 107833. PMID: 31935358
  9. Effect of solvent nature on propylene glycol oxidation with tert-butyl hydroperoxide over metal-organic framework Cr-MIL-101.  |  Torbina, V., et al. 2019. RSC Adv. 9: 25981-25986. PMID: 35531019
  10. Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.  |  Chen, Z., et al. 2022. Commun Biol. 5: 616. PMID: 35732814
  11. CREB Ameliorates Osteoarthritis Progression Through Regulating Chondrocytes Autophagy via the miR-373/METTL3/TFEB Axis.  |  Zhang, H., et al. 2021. Front Cell Dev Biol. 9: 778941. PMID: 35756079
  12. tert.-butyl hydroperoxide-mediated DNA base damage in cultured mammalian cells.  |  Altman, SA., et al. 1994. Mutat Res. 306: 35-44. PMID: 7512201
  13. Effect of extracellular ions and modulators of calcium transport on survival of tert-butyl hydroperoxide exposed cardiac myocytes.  |  Castro, GJ. and Bhatnagar, A. 1993. Cardiovasc Res. 27: 1873-81. PMID: 8275538

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Butyl hydroperoxide solution, 25 ml

sc-500948A
25 ml
$94.00

tert-Butyl hydroperoxide solution, 100 ml

sc-500948
100 ml
$229.00