Date published: 2026-2-27

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tert-Butyl bromoacetate (CAS 5292-43-3)

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Application:
tert-Butyl bromoacetate is a common alkylating agent
CAS Number:
5292-43-3
Purity:
98%
Molecular Weight:
195.05
Molecular Formula:
C6H11BrO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Common alkylating agent. Used in the synthesis of the collagenase inhibitor (S,S,R)-(−)-actinonin.(1)Building block for substituted t-butyl acetates.(2)Employed in the synthesis of a dihydropyranyl prelinker which was used, in turn, in an efficient polymer-assisted deprotection of oligosacchararides.(3)


tert-Butyl bromoacetate (CAS 5292-43-3) References

  1. Synthesis of fused heteroarylprolines and pyrrolopyrroles.  |  Jeannotte, G. and Lubell, WD. 2004. J Org Chem. 69: 4656-62. PMID: 15230586
  2. Efficient polymer-assisted strategy for the deprotection of protected oligosaccharides.  |  Tanaka, H., et al. 2006. Angew Chem Int Ed Engl. 45: 6349-52. PMID: 16917795
  3. Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors.  |  Sparaco, R., et al. 2022. Int J Mol Sci. 23: PMID: 36430281
  4. Recognition Site Modifiable Macrocycle: Synthesis, Functional Group Variation and Structural Inspection.  |  Fan, L., et al. 2023. Molecules. 28: PMID: 36771008
  5. Size Control and Biological Properties of PAMAM-Cored Multiarm Block Copolymers.  |  Yu, B., et al. 2023. ACS Appl Bio Mater. 6: 2426-2434. PMID: 37259528
  6. Reduction of the Renal Radioactivity of 111In-DOTA-Labeled Antibody Fragments with a Linkage Cleaved by the Renal Brush Border Membrane Enzymes.  |  Suzuki, H., et al. 2023. J Med Chem. 66: 8600-8613. PMID: 37322876
  7. Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors.  |  Shungube, M., et al. 2023. RSC Adv. 13: 18991-19001. PMID: 37362332
  8. The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones.  |  Ihnatenko, I., et al. 2023. PLoS One. 18: e0292946. PMID: 38032881
  9. Copper-Catalyzed Synthesis of Masked (Hetero)Aryl Sulfinates.  |  Merino, MR., et al. 2024. Org Lett. 26: 2817-2820. PMID: 38189248
  10. A Naphthoquinoline-Dione-Based Cu2+ Sensing Probe with Visible Color Change and Fluorescence Quenching in an Aqueous Organic Solution.  |  Kumar, A. and Chae, PS. 2024. Molecules. 29: PMID: 38398561
  11. Switchable Coacervate Formation via Amino Acid Functionalization of Poly(dehydroalanine).  |  Morrison, CA., et al. 2024. Biomacromolecules. 25: 2554-2562. PMID: 38426942
  12. Design, synthesis and activity evaluation of arctigenin derivatives with HDAC inhibition activity.  |  Jiang, X., et al. 2024. RSC Adv. 14: 9314-9325. PMID: 38510486
  13. Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader.  |  Carmona, AV., et al. 2024. Commun Chem. 7: 95. PMID: 38684887

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Butyl bromoacetate, 10 g

sc-253634
10 g
$28.00

tert-Butyl bromoacetate, 50 g

sc-253634A
50 g
$104.00