Date published: 2025-11-10

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tert-Butyl 6-Hydroxyhexanoate (CAS 73839-20-0)

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Alternate Names:
6-Hydroxy-hexanoic Acid 1,1-Dimethylethyl Ester
Application:
tert-Butyl 6-Hydroxyhexanoate is An aliphatic tert-butyl ester with a terminal hydroxyl
CAS Number:
73839-20-0
Molecular Weight:
188.26
Molecular Formula:
C10H20O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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tert-Butyl 6-Hydroxyhexanoate is a simple aliphatic tert-butyl ester with a terminal hydroxyl group. This compound presents a useful organic fragment for synthesis, and has been utilized in the synthesis of a phosphorylcholine ester for studies immunological studies on phosphorylcholine-binding immunoglobulins. In chemical synthesis, the tert-butyl group in the compound plays a significant role. It provides steric hindrance, which can protect the ester linkage from hydrolysis and other reactions, making the compound more stable under certain conditions. This stability is advantageous in multi-step synthetic processes, where selective reactivity is needed.


tert-Butyl 6-Hydroxyhexanoate (CAS 73839-20-0) References

  1. Liposomal formulation of retinoids designed for enzyme triggered release.  |  Pedersen, PJ., et al. 2010. J Med Chem. 53: 3782-92. PMID: 20405849
  2. Precise Synthesis, Properties, and Structures of Cyclic Poly(ε-caprolactone)s.  |  Xiang, L., et al. 2018. Polymers (Basel). 10: PMID: 30966611
  3. Progress toward the Development of Glycan-Based Vaccines against Campylobacteriosis.  |  Cloutier, M. and Gauthier, C. 2021. ACS Infect Dis. 7: 969-986. PMID: 32579844
  4. E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points.  |  Bricelj, A., et al. 2021. Front Chem. 9: 707317. PMID: 34291038

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Butyl 6-Hydroxyhexanoate, 2 g

sc-213004
2 g
$367.00