Date published: 2026-2-8

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tert-Butyl 4-(4-iodophenyl)piperazine-1-carboxylate (CAS 151978-66-4)

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CAS Number:
151978-66-4
Molecular Weight:
388.24
Molecular Formula:
C15H21IN2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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tert-Butyl 4-(4-iodophenyl)piperazine-1-carboxylate is a white or nearly white solid that dissolves in a range of organic solvents, including dimethyl sulfoxide, methanol, and acetonitrile. The compound has garnered interest for its prospective applications in diverse research areas and industries, particularly in material sciences. Within this field, tert-Butyl 4-(4-iodophenyl)piperazine-1-carboxylate is used as a starting material for creating a variety of polymers and materials that contain functionalized piperazine.


tert-Butyl 4-(4-iodophenyl)piperazine-1-carboxylate (CAS 151978-66-4) References

  1. Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.  |  Ghosh, B., et al. 2010. J Med Chem. 53: 1023-37. PMID: 20038106
  2. Further delineation of hydrophobic binding sites in dopamine D(2)/D(3) receptors for N-4 substituents on the piperazine ring of the hybrid template 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol.  |  Ghosh, B., et al. 2010. Bioorg Med Chem. 18: 5661-74. PMID: 20605099
  3. Transient excited-state absorption and gain spectroscopy of a two-photon absorbing probe with efficient superfluorescent properties.  |  Belfield, KD., et al. 2012. J Phys Chem C Nanomater Interfaces. 116: 11261-11271. PMID: 22707998
  4. Multifunctional D2/D3 agonist D-520 with high in vivo efficacy: modulator of toxicity of alpha-synuclein aggregates.  |  Modi, G., et al. 2014. ACS Chem Neurosci. 5: 700-17. PMID: 24960209
  5. Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors.  |  De Clercq, DJH., et al. 2019. ACS Med Chem Lett. 10: 1549-1553. PMID: 31749909

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Butyl 4-(4-iodophenyl)piperazine-1-carboxylate, 1 g

sc-264357
1 g
$61.00

tert-Butyl 4-(4-iodophenyl)piperazine-1-carboxylate, 5 g

sc-264357A
5 g
$245.00