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tert-Amyl methyl ether (CAS 994-05-8)

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Alternate Names:
1,1-Dimethylpropyl methyl ether; Methyl 2-methyl-2-butyl ether; Methyl tert-pentyl ether; TAME
CAS Number:
994-05-8
Purity:
≥96%
Molecular Weight:
102.17
Molecular Formula:
C6H14O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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tert-Amyl methyl ether (TAME) is a volatile organic compound (VOC) used in a variety of industrial and laboratory applications. For example, it is used as a fuel additive, as a solvent for paints and coatings, and as a laboratory reagent for synthesizing other compounds. Additionally, its neuroprotective effects are due to its ability to modulate the activity of several neurotransmitters, such as glutamate, dopamine, and norepinephrine. Moreover, studies have reported antioxidant, anti-inflammatory, and anti-cancer effects of TAME.


tert-Amyl methyl ether (CAS 994-05-8) References

  1. A physiological model for tert-amyl methyl ether and tert-amyl alcohol: hypothesis testing of model structures.  |  Collins, AS., et al. 1999. Toxicol Sci. 49: 15-28. PMID: 10367338
  2. Biotransformation and kinetics of excretion of tert-amyl-methyl ether in humans and rats after inhalation exposure.  |  Amberg, A., et al. 2000. Toxicol Sci. 55: 274-83. PMID: 10828258
  3. Results of long-term carcinogenicity bioassays on tert-amyl-methyl-ether (TAME) and di-isopropyl-ether (DIPE) in rats.  |  Belpoggi, F., et al. 2002. Ann N Y Acad Sci. 982: 70-86. PMID: 12562629
  4. Determination of low level methyl tert-butyl ether, ethyl tert-butyl ether and methyl tert-amyl ether in human urine by HS-SPME gas chromatography/mass spectrometry.  |  Scibetta, L., et al. 2007. Anal Chim Acta. 581: 53-62. PMID: 17386425
  5. Toxicokinetics of methyl tert-butyl ether (MTBE) and tert-amyl methyl ether (TAME) in humans, and implications to their biological monitoring.  |  Vainiotalo, S., et al. 2007. J Occup Environ Hyg. 4: 739-50. PMID: 17668360
  6. Comprehensive experimental and theoretical study of chemical equilibria in the reacting system of the tert-amyl methyl ether synthesis.  |  Heintz, A., et al. 2007. J Phys Chem B. 111: 10975-84. PMID: 17722908
  7. Single-walled carbon nanotubes as an effective adsorbent in solid-phase microextraction of low level methyl tert-butyl ether, ethyl tert-butyl ether and methyl tert-amyl ether from human urine.  |  Rastkari, N., et al. 2009. J Chromatogr B Analyt Technol Biomed Life Sci. 877: 1568-74. PMID: 19395320
  8. Isotopic fractionation of methyl tert-butyl ether suggests different initial reaction mechanisms during aerobic biodegradation.  |  McKelvie, JR., et al. 2009. Environ Sci Technol. 43: 2793-9. PMID: 19475952
  9. ETBE (ethyl tert butyl ether) and TAME (tert amyl methyl ether) affect microbial community structure and function in soils.  |  Bartling, J., et al. 2011. J Hazard Mater. 187: 488-94. PMID: 21288640
  10. Vapor intrusion risk of fuel ether oxygenates methyl tert-butyl ether (MTBE), tert-amyl methyl ether (TAME) and ethyl tert-butyl ether (ETBE): A modeling study.  |  Ma, J., et al. 2017. J Hazard Mater. 332: 10-18. PMID: 28279869
  11. A New control structure for tert-amyl methyl ether production using reactive distillation.  |  Kharaji, S., et al. 2020. ISA Trans. 97: 53-66. PMID: 31358298
  12. Biodegradation of the gasoline oxygenates methyl tert-butyl ether, ethyl tert-butyl ether, and tert-amyl methyl ether by propane-oxidizing bacteria.  |  Steffan, RJ., et al. 1997. Appl Environ Microbiol. 63: 4216-22. PMID: 9361407
  13. Exposure to methyl tert-butyl ether and tert-amyl methyl ether from gasoline during tank lorry loading and its measurement using biological monitoring.  |  Vainiotalo, S., et al. 1998. Int Arch Occup Environ Health. 71: 391-6. PMID: 9766912

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Amyl methyl ether, 5 ml

sc-251125
5 ml
$51.00

tert-Amyl methyl ether, 100 ml

sc-251125A
100 ml
$268.00