Terbinafine-d7 Hydrochloride (CAS 1185240-27-0)

Terbinafine-d7 hydrochloride is a deuterated form of terbinafine, utilized extensively in scientific research. This compound, characterized by the substitution of hydrogen atoms with deuterium at seven specific positions, serves as an invaluable tool in the field of analytical chemistry. Its primary use is as an internal standard in sophisticated techniques like mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. This isotopic labeling enables precise quantification and tracking of chemical transformations in various experimental setups. The specific mechanism of action of Terbinafine-d7 hydrochloride mirrors that of its non-deuterated analog, which involves inhibiting squalene epoxidase, a key enzyme in the fungal ergosterol biosynthesis pathway. By inhibiting this enzyme, the compound disrupts critical cellular processes in fungi, which is a focal point of interest in studies related to fungal biochemistry and physiology. Research utilizing Terbinafine-d7 hydrochloride is geared towards understanding these biochemical pathways and exploring fungal behavior under exposure to enzyme inhibitors. This provides deep insights into fungal adaptation and resistance mechanisms, greatly enhancing the knowledge base in fungal biology and enzymatic inhibition