Temozolomide-d3 (CAS 208107-14-6)

Temozolomide-d3 is a deuterated analog of Temozolomide that is used in the field of analytical chemistry, particularly in the development of mass spectrometric methods. Its incorporation of three deuterium atoms makes it a suitable internal standard for quantifying Temozolomide through mass spectrometry, due to the minimal difference in chemical behavior compared to the non-deuterated form while providing a distinct mass difference. Research involving Temozolomide-d3 often focuses on the optimization of detection methods for Temozolomide, ensuring accurate and precise measurement of the compound in complex biological matrices. The use of Temozolomide-d3 also extends to studies on the kinetics and metabolic fate of Temozolomide, where it can be used to track the absorption, distribution, metabolism, and excretion of the compound. Furthermore, it is instrumental in the calibration of instruments and validation of analytical procedures, which are critical for ensuring the reliability of data in research applications.