Date published: 2026-3-19

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Temephos (CAS 3383-96-8)

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CAS Number:
3383-96-8
Purity:
≥97%
Molecular Weight:
466.47
Molecular Formula:
C16H20O6P2S3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Temephos is a widely used larvicide, mainly employed for its larvicidal properties. It exists as a white crystalline solid or a liquid form, transitioning to a liquid state above 87°F. Additionally, Temephos is classified as an organic sulfide, specifically a diphenyl sulfide derivative in which the hydrogen atoms on the para position of each phenyl group are replaced by a (dimethoxyphosphorothioyl)oxy group. Temephos exhibits diverse roles, functioning as an inhibitor of acetylcholinesterase (EC 3.1.1.7), an acaricide, an agrochemical, and an ectoparasiticide. It falls under the category of organic thiophosphates, organothiophosphate insecticides. The compound originates from a 4,4′-thiodiphenol precursor.


Temephos (CAS 3383-96-8) References

  1. Temephos resistance in Aedes aegypti in Colombia compromises dengue vector control.  |  Grisales, N., et al. 2013. PLoS Negl Trop Dis. 7: e2438. PMID: 24069492
  2. Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.  |  George, L., et al. 2015. PLoS Negl Trop Dis. 9: e0004006. PMID: 26371470
  3. Effects of prenatal exposure to temephos on behavior and social interaction.  |  Martins Laurentino, AO., et al. 2019. Neuropsychiatr Dis Treat. 15: 669-673. PMID: 30880993
  4. Detrimental effects of temephos on male fertility: An in vitro study on a mouse model.  |  Kim, SH., et al. 2020. Reprod Toxicol. 96: 150-155. PMID: 32574676
  5. Human Biotransformation Pathway of Temephos Using an In Silico Approach.  |  Reyes-Chaparro, A., et al. 2020. Chem Res Toxicol. 33: 2765-2774. PMID: 33112607
  6. Toxicokinetics of temephos after oral administration to adult male rats.  |  Verdín-Betancourt, FA., et al. 2021. Arch Toxicol. 95: 935-947. PMID: 33471133
  7. Temephos Decreases Sperm Quality and Fertilization Rate and Is Metabolized in Rat Reproductive Tissues at Low-Dose Exposure.  |  Ramos-Flores, Á., et al. 2021. Toxicol Sci. 184: 57-66. PMID: 34382084
  8. Larvicidal efficacy of temephos impregnated onto kenaf cellulose nanofibre to control Aedes aegypti (Diptera: Culicidae) larvae.  |  Pengiran, H., et al. 2021. Trop Biomed. 38: 453-461. PMID: 34608119
  9. The effects of temephos, permethrin and malathion selection on the fitness and fecundity of Aedes aegypti.  |  Gleave, K., et al. 2022. Med Vet Entomol. 36: 56-65. PMID: 34751971
  10. Effects of Temephos (Abate®), Spinosad (Natular®), and Diflubenzuron on the Survival of Cyclopoid Copepods.  |  Grunert, R., et al. 2022. Am J Trop Med Hyg. 106: 818-822. PMID: 35073509
  11. Temephos, an organophosphate larvicide for residential use: a review of its toxicity.  |  Martínez-Mercado, JP., et al. 2022. Crit Rev Toxicol. 52: 113-124. PMID: 35608007
  12. First national-scale evaluation of temephos resistance in Aedes aegypti in Peru.  |  Palomino, M., et al. 2022. Parasit Vectors. 15: 254. PMID: 35818063
  13. Detection of Ace-1 Mutation in Temephos-Resistant Aedes aegypti L. in West Sumatra, Indonesia.  |  Rahayu, R., et al. 2022. Pak J Biol Sci. 25: 816-821. PMID: 36098083

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Temephos, 100 mg

sc-258193
100 mg
$153.00