Teijin compound 1 (CAS 226226-39-7)
Alternate Names:
Teijin compound 1 hydrochloride
CAS Number:
226226-39-7
Molecular Weight:
476.32
Molecular Formula:
C21H21ClF3N3O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A potent chemokine CCR2b receptor antagonist (IC50 = 180 nM). Shown to potently inhibit cell chemotaxis induced by MCP-1 (EC50 = 24 nM).
Teijin compound 1 (CAS 226226-39-7) References
Moree et al (2004) Small molecule antagonists of the CCR2b receptor. Part 2: discovery process and initial structure-activity relationships of diamine derivatives. Bioorg.Med.Chem.Letts. 14 5413. Moree et al (2008) Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg.Med.Chem.Letts. 18 1869. Hall et al (2009) Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5. Mol.Pharmacol. 75 1325.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Teijin compound 1, 5 mg | sc-301864 | 5 mg | $124.00 | |||
Teijin compound 1, 25 mg | sc-301864A | 25 mg | $493.00 |